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Tri-Luma® Cream for Hyperpigmentation

Hydroquinone 2% / 4% + Tretinoin 0.012% / 0.05% + Fluocinolone 0.01%

(44 customer reviews)

From USD $35.00

Discover the transformative power of Tri-Luma® Cream, a unique triple-combination therapy specifically designed to combat hyperpigmentation. This high-quality topical treatment:

  • Effectively lightens dark spots and discolorations caused by conditions such as melasma and freckles, thanks to its active ingredient Hydroquinone
  • Promotes skin renewal and exfoliation with Tretinoin, a synthetic form of Vitamin A that accelerates skin cell growth
  • Reduces inflammation and potential skin irritation with Fluocinolone Acetonide, a medium-potency anti-inflammatory agent
Size: 15g / 0.53oz, 20g / 0.7oz
Brand name: Lumiquin, Lumacip Plus, Refaquin, Retrieve
Title Range Discount
Items: 2 - 4 5%
Items: 5 - 8 10%
Items: 9 + 15%


What is Tri-Luma® Cream?

Tri-Luma® Cream is a product of Galderma, a reputable pharmaceutical company known for its high-quality skincare products. It’s designed for short-term use and should always be used in conjunction with sun-avoidance measures for optimal results.

Available for purchase online from OKDERMO, this cream is accessible to customers in the USA, UK, Canada, Mexico, and more. With competitive pricing and reliable shipping, OKDERMO ensures that your journey to healthier, more radiant skin is just a click away. Experience the benefits of Tri-Luma® Cream and start your journey to a more even-toned, radiant complexion today!

Tri-Luma® Cream is a unique, high-quality topical treatment designed to combat skin hyperpigmentation. This triple-combination therapy is specifically formulated to address conditions such as melasma, dark spots, freckles, and other dark discolorations on the skin. The cream works by lightening the skin, reducing inflammation, and increasing exfoliation.

Tri-Luma Cream is a product of Galderma, a reputable pharmaceutical company known for its high-quality skincare products. The cream is designed for short-term use, typically not exceeding five months in a row, and should always be used in conjunction with
sun-avoidance measures, such as using strong sunscreens and wearing protective clothing.

The effectiveness of Tri-Luma Cream can be seen in the before and after pictures in the product gallery. These pictures show a noticeable reduction in hyperpigmentation, with the skin appearing more even-toned and radiant.

Testimonials from users also attest to the effectiveness of the product. Many users have reported seeing improvements in their skin condition within a few weeks of using the cream.

Active Ingredients of Tri Luma Cream

Tri-Luma Cream is composed of three active ingredients: Hydroquinone, Tretinoin, and Fluocinolone Acetonide. Each of these components plays a crucial role in the effectiveness of the cream.

  • Hydroquinone 4%: This is a skin depigmenting agent that flawlessly blocks melanin production, evening out skin tone. It inhibits the enzyme tyrosinase, which controls melanin production, thus reducing the formation of melanin by melanocytes. As melanin production decreases, the darkened skin gradually lightens to match the normal skin color.
  • Tretinoin 0.05%: Tretinoin is a synthetic form of Vitamin A that renews the skin. It binds to specific retinoic acid receptors in the nucleus of skin cells, affecting how these cells behave. This regulates cell growth and differentiation and also has anti-inflammatory properties. Tretinoin accelerates skin epithelial cell proliferation and epithelial differentiation, promoting the growth of new skin cells and lightening the skin.
  • Fluocinolone Acetonide 0.01%: This is a medium potency anti-inflammatory agent that concentrates in the skin but does not enter the blood circulation, thereby minimizing systemic effects. Fluocinolone Acetonide reduces the risk of developing contact dermatitis that may be caused by other components of the cream, like hydroquinone and tretinoin.

Benefits of Tri-Luma Cream

Tri-Luma® Cream offers several benefits, making it a preferred choice for treating hyperpigmentation. These benefits include:

  • Treating Dark Spots: The cream is effective in treating dark spots caused by melasma, a skin condition that causes brown patches to appear due to excess melanin production.
  • Exfoliating the Skin: Tretinoin, one of the active ingredients in Tri-Luma® Cream, promotes the shedding of old hardened skin cells and the growth of new ones, thereby exfoliating the skin.
  • Anti-Inflammatory Properties: The Fluocinolone Acetonide in Tri-Luma® Cream has anti-inflammatory properties that help to heal the skin and reduce inflammation.

How to Use Tri-Luma Cream

Using Tri-Luma® Cream properly is crucial to achieving the desired results. Here is a step-by-step guide on how to apply the cream:

  • Wash your face gently with a mild cleanser and warm water, then pat your skin dry.
  • Apply a small amount (pea-sized drop) of cream to your clean, dry face.
  • Always apply the cream about 30 minutes before bedtime.
  • Rub the cream gently into the skin, ensuring to spread it evenly.
  • Do not overuse the cream as this will not result in better results.
  • Ensure to rub in fully so your skin absorbs the cream.
  • Avoid applying the cream to the corners of your nose, mouth, eyes, or open wounds as it may cause irritation.

Remember, it’s essential to use the cream in conjunction with sun-avoidance measures. This includes using sunscreen with a high SPF, wearing protective clothing, and avoiding direct sunlight exposure, especially between 10 AM and 2 PM when the sun’s rays are most intense.

Where to Buy Tri-Luma® Cream

Tri-Luma® Cream is available for purchase online from various platforms. One reliable source is OKDERMO, an online skincare and beauty store that offers a wide range of skincare products. They provide shipping to various countries, including the USA, UK, Canada, and Mexico.

Whether you’re in Canada and looking to buy Tri-Luma Cream online, or you’re in Mexico and want to order Tri-Luma® Cream online, OKDERMO has got you covered. They offer a seamless and secure online shopping experience, ensuring that your product reaches you in the best condition.

Tri-Luma Cream Price

The price of Tri-Luma® Cream can vary depending on the platform you choose to purchase from. However, OKDERMO offers competitive pricing for this product. It’s always advisable to compare prices on different online platforms to ensure you’re getting the best price on Tri-Luma® Cream.

Tri-Luma® Cream Side Effects

While Tri-Luma® Cream is generally safe to use, some users may experience side effects. These can include skin redness, peeling, dryness, burning, or itching. If these symptoms persist or worsen, it’s advisable to stop using the product and consult a healthcare professional.

In rare cases, the cream may cause a blue-black darkening of the skin. If this occurs, stop using the cream immediately and seek medical attention.

Remember, it’s always best to consult with a healthcare professional before starting any new skincare regimen.

In conclusion, Tri-Luma® Cream is a potent solution for hyperpigmentation. Its unique combination of active ingredients works synergistically to lighten the skin, reduce inflammation, and promote skin renewal. Whether you’re dealing with melasma, freckles, or other forms of hyperpigmentation, Tri-Luma® Cream offers a promising solution.

Resources (updated on May 18, 2023)

Additional Information


  • Hydroquinone 2%
  • Tretinoin 0.025%
  • Fluocinolone acetonide 0.01%

Other ingredients: butylated hydroxytoluene, cetyl alcohol, citric acid, glycerin, glyceryl stearate, magnesium aluminum silicate, methyl gluceth-10, methylparaben, PEG-100 stearate, propylparaben, purified water, sodium metabisulfite, stearic acid, and stearyl alcohol.