Agefine® Anti-Ageing Cream

Skin Whitening L-Glutathione + Glycolic Acid + Shea Butter

4.71 out of 5

(7 customer reviews)

USD $29.00 (EUR €27.55)

✓ Removes all types of skin blemishes: dark spots, age spots, wrinkles, freckles

✓ Works on all layers of skin to cause lasting changes

✓ With a sunscreen lotion to protect your skin from sunburn

✓ Improves skin elasticity

Agefine® Glutathione cream intensive whitening facial cream for a beautiful radiant skin ideal with a cutting edge innovation of Glutathione and Vitamin C for perfect bright and beautiful skin results. With Glycolic acid, Shea butter, Vitamin E, Vitamin C, Bearberry Extract, Licorice Extract, and Niacinamide skin appears more radiant and consistent in color.

Size: 20g / 0.7oz
Title Range Discount
Items: 2 - 4 5%
Items: 5 - 8 10%
Items: 9 + 15%


What is L-Glutathione Cream Agefine®

Agefine® cream is a skin whitening cream enriched with the key ingredient L-Glutathione, and other potent components for flawless skin, such as Glycolic acid, Shea butter, Vitamin E, Vitamin C, Bearberry Extract, and Licorice Extract coupled with a very powerful body-protecting chemical. Agefine® cream gives you fair, smooth, and perfect skin as one of the best natural skin whitening creams available on the market. Apply cream throughout the face and neck regularly in the morning and evening.

L-Glutathione (GSH) is an antioxidant in plants, animals, fungi, and some bacteria and archaea. Glutathione is capable of preventing damage to important cellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides, and heavy metals. It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side-chain and the amine group of cysteine, and the carboxyl group of cysteine is attached by a normal peptide linkage to a glycine.

Agefine® Anti-Ageing Cream is a topical cream used for skin peeling, whitening, and moisturizing. It contains a combination of potent antioxidants and Shea butter. Additionally, the Agefine formula incorporates lotion sunscreen to protect against photodamage.

Glutathione is the main active ingredient. It has potent antioxidant properties that treat hyperpigmentation, dark spots, sun blemishes, and melasma. Moreover, Agefine is not only a skin discoloration treatment. It contains glycolic acid, which has age-defying activity, reducing wrinkles and fine lines appearances. In addition to its anti melanin activity, glutathione is a powerful antioxidant that creates positive changes in complexion. It promptly hydrates the deep skin layer, leading to a soft appearance. It maintains an even skin color, provides a smooth, bright, and silky tone.

What is glutathione?

It is a naturally occurring antioxidant. It mediates vital biological processes, including tissue building, producing chemicals and proteins. Additionally, glutathione is a necessary antioxidant for proper immune system functioning. The liver produces glutathione, which travels in systemic circulation to cancel out free radicals.

In the skin, glutathione can work wonders. It blocks free radicals from damaging skin cells or collagen. It protects the skin from photodamage and environmental pollution. A randomized study included 30 subjects to confirm the skin effects of glutathione, glycine, and cysteine. The study evaluated skin firmness, elasticity, and whiteness after antioxidants treatment in comparison with placebo lotion. The results showed a significant decline in melanin production with glutathione use. Owing to its potent antioxidant properties, subjects treated with glutathione had a reduction in wrinkles, fine lines. Moreover, they had increased elasticity and smoothness over subjects treated with placebo lotion.

How to use Agefine age-defying cream?

Experts agree that an efficient antiwrinkle skincare routine includes potent antioxidants during the day and retinoids and moisturizers at night. Agefine contains sunscreen lotion in addition to ingredients that have a good safety profile. Application twice a day is safe and efficient.

A good rule of thumb is to clean the face from debris accumulated at night or makeup, tone, and apply the cream.

Anti-wrinkle and age-defying properties

As the largest organ with vast exposure to external and internal damaging factors, the skin is most prone to aging than other organs. When a skin ages, it loses its elasticity, firmness, and thickness.
Aging involves modifications in connective tissue and cellular regeneration that manifest as a rough-textured appearance and wrinkles. 80% of skin aging mechanisms are due to photodamage. UV light exposure accelerates the aging process. So, the skin not only suffers intrinsic aging, which is common to all organs, but it also suffers extrinsic aging.

One way UV light speeds up aging is by enhancing free radical production. Free radicals are naturally occurring compounds. Due to their unstable nature, free radicals cause DNA and protein damage. The body uses antioxidants to minimize the damage created by free radicals. Aging is also associated with dry skin because skin layers become unable to maintain water molecules.

Glutathione and glycolic acid are potent antioxidants that balance oxidative stress caused by free radicals, while shea butter is an efficient moisturizer that increases antioxidants’ efficiency and maintains skin hydration.

Details about Glutathione Cream

Glutathione plays an important role in preventing oxidative damage to the skin. In addition to its many recognized biological functions, glutathione has also been associated with skin lightening ability. The role of glutathione as a skin whitener was discovered as a side effect of large doses of glutathione. Glutathione utilizes different mechanisms to exert its action as a skin whitening agent at various levels of melanogenesis. It inhibits melanin synthesis by means of stopping the neurotransmitter precursor L-DOPA’s ability to interact with tyrosinase in the process of melanin production. Glutathione inhibits the actual production as well as agglutination of melanin by interrupting the function of L-DOPA.

Another study found that glutathione inhibits melanin formation by direct inactivation of the enzyme tyrosinase by binding and chelating copper within the enzyme’s active site. Glutathione’s antioxidant property allows it to inhibit melanin synthesis by quenching free radicals and peroxides that contribute to tyrosinase activation and melanin formation. Its antioxidant property also protects the skin from UV radiation and other environmental as well as internal stressors that generate free radicals that cause skin damage and hyperpigmentation.

In most mammals, melanin formation consists of eumelanin (brown-black pigment) and pheomelanin ( yellow-red pigment) as either mixtures or copolymers. An increase in glutathione level may induce the pigment cell to produce pheomelanin instead of eumelanin pigments. Research by Te-Sheng Chang found the lowest levels of reduced glutathione to be associated with eumelanin-type pigmentation, whereas the highest ones were associated with pheomelanin. As a result, it is reasonable to assume that the depletion of glutathione would result in eumelanin formation. Prota observed that decreased glutathione concentration led to the conversion of L-Dopaquinone to Dopachrome, increasing the formation of brown-black pigment (eumelanin).


L-Glutathione, Glycolic acid, Shea butter, Vitamin E, Vitamin C, Bearberry Extract, Licorice Extract, Acrylates/C10-30, Alkyl Acrylate, Crosspolymer, Diacetyl Boldine-1000 ppm, Caprylic/Capric Triglyceride, Stearic Acid, Glycerin, Glycerol Mono Stearate, PEG-100 Stearate, Niacinamide, Cetyl Alcohol, Perfume, Dimethicone, Lactic Acid, Potassium, Hydroxide, Titanium Dioxide, Sodium Methylparaben, Sodium Propylparaben, EDTA Butylated Hydroxytoluene and Water.

7 reviews for Agefine® Anti-Ageing Cream

  1. 5 out of 5


    In 20+ years of searching for eczema relief, this is it. Hands down (the place where I have most of my eczema) the best topical cream to date. Waste no more time with steroids or prescriptions. Also, try internal glutathione capsules! They work!

  2. 5 out of 5

    Clara Sapkin

    Nothing is better than glutathione on the skin, fairer skin even in one week, but this one is not bleach but making the skin glowing. I’ve tried all kinds of glutathione creams. Agefine product is one of the best.

  3. 5 out of 5

    Jade T’saura

    Not a pleasant smell but quite effective for my issue

  4. 4 out of 5

    Louise DeNoune

    Non-greasy glutathione cream with the sunscreen and you only need a pea-size amount. Great value! It is quite hard to find a great glutathione cream nowadays, this one is worth it, recommend!

  5. 5 out of 5

    Miss Mocha Latte

    This cream has become my birthday gift to my closest friends! It lightens red and dark areas and so much more. My dermatologist wanted to remove a skin growth because it was gaining height and becoming noticeable. I avoid all but urgent surgery and said I’d investigate alternatives. I read the reviews and ordered. This cream shrunk it down so it’s really small. My friends report similar results … it’s not gone, but it’s not noticeable. I recommend this product for general skincare. My doctor reviewed the contents and deemed them safe for my skin. He said that given my results it is a very reasonably priced cream. Continue to apply it.

  6. 4 out of 5

    Jamie C.

    It truly brings up my skin tone for a foundation-free look. Just as it is described! Works well with my regular skincare. Delivery waiting time is quite long, that’s why 4 stars

  7. 5 out of 5

    Ina brigante

    Nice easy shopping process fast delivery no problems ordering or delivering. Used on my husband’s dark spots so far it has started lighting the dark spots he has on his skin. no adverse reactions would recommend to others. He has had no side effects of this product so far.

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