Description
What is Triohale® Inhaler?
Triohale Inhaler is used for the treatment of chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked). It helps in relaxing the muscles of the air passages and making it easier to breathe. It relieves coughing, wheezing and feeling short of breath.
Asthma is a persistent respiratory condition characterized by narrowed airways, inflamed bronchioles, excess mucus trapping, and breathing difficulties. Chronic obstructive pulmonary disease (COPD) is an incurable condition that presents with two chronic lung conditions known as emphysema and chronic bronchitis.
COPD (chronic obstructive pulmonary disease) is a group of lung diseases that cause breathing difficulties. COPD is caused by swelling of the airways that carry air in and out of the lungs. Triohale Inhaler relaxes the muscles of these airways and widens it. This makes you breathe easy and gives relief from symptoms such as tightness in your chest, shortness of breath, wheezing and coughing. Avoid smoking and minimise your exposure to pollution, dust and fumes. Along with that, a little exercise each day can help you stay strong. Talk to your doctor about how much exercise is good for you.
The long-acting antimuscarinic medications can induce bronchodilation by inhibiting the muscarinic receptors within the bronchioles. Tiotropium is the antimuscarinic agent used in the manufacturing of Triohale inhalers. This class of drugs is given another name, anticholinergic medications.
The localized effect of Formoterol can make the bronchioles dilated. They belong to the drug class known as beta two adrenergic receptor agonists. The studies have shown that Formoterol shows 200times more affinity towards the beta two receptors when compared with beta one receptors. Therefore Formoterol can agonist the activity of beta two receptors within the bronchioles. As there are few beta two receptors located in the heart muscles, the drug can also affect the cardiac system. According to the results obtained from the in-vitro studies, they show that Formoterol can block the release of chemical mediators like histamine. Therefore it can suppress the extravasation of plasma albumin.
Ciclesonide is a corticosteroid that belongs to the sub-category known as glucocorticoids. It can reduce the signs and symptoms of inflammation and relax the airways. Ciclesonide is a prodrug and gets converted to its active metabolite once inhaled.
Side effects of Triohale® Inhaler
Fungal infections of the oral cavity as corticosteroids suppress immunity and damage normal flora of the oral cavity, Nausea and vomiting, Headache, Sore throat, Cough, Infections of the respiratory tract, Myalgia and arthralgia, Tachycardia is due to the activation of beta two receptors within the heart muscles.
Precautions:
- If you are a person who is allergic to lactose or has experienced lactose intolerance, please inform the details to your doctor.
- Do not allow children to use the inhalers without a doctor’s order. This inhaler is not recommended for children below 6years.
- If you get pregnant or breastfeed a baby, inform the physician.
- There are rare instances where the patients may experience chest tightness after inhaler use. If these symptoms last longer, take immediate medical advice.
- Measure normal serum potassium levels, as there is a risk of lowering serum potassium levels.
- If you are a known patient with hypertension, diabetes, hypokalemia, chickenpox, measles, liver disease, or heart disease, take precautions when using Tiohale inhalers.
- Ciclesonide + Formoterol + Tiotropium can interact with grapefruit juice so avoid consuming grapefruit juice while using Tiohale inhaler.
- Ciclesonide + Formoterol + Tiotropium can interact with certain medications. If you consume any other medicines, please be cautious and inform the doctor to avoid drug interactions.
- The action of alcohol together with Ciclesonide + Formoterol + Tiotropium is unknown. Therefore take precautions when you use alcohol.
How to use Triohale® Inhaler
Shake the inhaler well before using it. Seal the inhaler’s mouthpiece inside the mouth and press the canister to administer the required dose. Now hold your breath inside for a few seconds and exhale well. Perform the same steps until you take the needed amount.
