What is Duolin® Inhaler?
Duolin inhalers are currently used as a symptom reliever in COPD treatment. Dolin inhalers are manufactured with two drugs called Levosalbutamol and Ipratropium Bromide. The combined effect of these two drugs may help COPD patients to live everyday life.
COPD is believed to be a chronic lung condition where the original lung functions cannot restore. Therefore, inhalers can help the patients to get rid of the discomfort. COPD is mainly characterized by two conditions called emphysema and chronic bronchitis. The inflammation and swelling of the airways may reduce the lumen size. So the air can’t move freely within the bronchioles. Duolin inhalers can suppress the inflammation to make it easy for the patient to breathe in and out.
The results of the inhaler usage may become noticeable after a few days. The best results will be apparent after a few weeks. The studies have proven that inhalers are recommended to use regularly. The consumers may feel comfortable after a few weeks of inhaler usage, but the inhaler usage must be continued throughout the life to prevent worsening and relapses. Duolin inhalers are manufactured to use as maintenance medication. So this product will not help during acute phases. The sudden symptoms cannot be relieved with the use of Duolin Inhalers.
Levosalbutamol belongs to a drug class called beta two adrenergic activators. Beta two receptors are located on the smooth muscles of the bronchioles. When the drug molecules bind with the beta two receptors, they activate the action of these receptors. The stimulation of the beta two receptors results in the activation of adenylate cyclase, resulting in a lower level of intracellular calcium. Therefore this process involves relaxing the airways.
There are several categories of anticholinergic drugs used to treat respiratory conditions. Ipratropium bromide is also an anticholinergic agent, which blocks acetylene choline’s action. Acetylene choline is one of the neurotransmitters released in the lungs. Lower acetylcholine levels involve in raising the level of cyclic guanosine monophosphate.
Ipratropium Bromide is an anticholinergic (parasympatholytic) agent, which appears to inhibit vagally-mediated reflexes by antagonizing the action of acetylcholine, the transmitter agent released at neuromuscular junctions in the lungs. Anticholinergics prevent increases in intracellular concentration of cyclic guanosine monophosphate (cGMP), which are caused by the interaction of acetylcholine with the muscarinic receptor on bronchial smooth muscle.
Side effects of Duolin® Inhaler
People may experience a few side effects, but they resolve when the body gets adapted to these changes. But if there are serious side effects, consult medical opinion immediately: Dry mouth, Cough, Tremors of the extremities, Headache, Palpitations, Cramps in leg muscles.
How to use Duolin® Inhaler
Shake the inhaler and get ready for the inhalation. Seal the mouthpiece inside the mouth and keep the head straight. Take a breath and exhale fully. Now press the inhaler to release the medications. Breathe in well and hold your breath for seconds. Repeat the same until the prescribed doses are added. Rinse the oral cavity well with water after each inhalation.
- Avoid consuming alcohol, as they course excessive drowsiness when taken together.
- Duolin inhalers are contraindicated in pregnancy. Animal studies show the ingredients may affect the fetus badly.
- It is probably safe to use the inhalers during breastfeeding, but consult your physician before deciding.
- Duolin inhalers are only designed to use as an inhaler. So never take it orally.
- Be alert about paradoxical bronchospasms, and it will be a life-threatening situation when not treated immediately.
- Do not use extra doses in between time intervals. Follow the doctor’s order throughout the inhaler usage.