What are Formoterol + Tiotropium Rotacaps?
Duova® Rotacaps have been manufactured targeting patients who suffer from the chronic obstructive pulmonary disorder. These Rotacaps are composed of two medications known as Tiotropium Bromide and Formoterol. Combining these two medications helps relax the airway and resolve symptoms associated with COPD.
Chronic obstructive pulmonary disorder is a lung condition characterized by two different conditions known as chronic bronchitis and emphysema. The combination of these two disorders results in narrowed airways and breathing problems. COPD is believed to be a chronic inflammatory lung condition with no exact treatment for the disease. Nuova Rotacaps can suppress the symptoms and discomfort associated with the condition. Therefore it is recommended to use Duova Rotacaps as a maintenance medication. This product is not recommended to use during acute episodes.
Tiotropium Bromide belongs to the anticholinergic drug class and is a form of long-acting medication. Bronchial smooth muscles are composed of muscarinic receptors. Tiotropium Bromide travels the respiratory passage and binds with the muscarinic receptors within the airways. At the same time, Tiotropium Bromide can inhibit the action of cholinergic receptors resulting in diminished Broncho constrictive effects. Tiotropium Bromide can act for a longer duration as it takes more time to get dislodged from the muscarinic receptors. So the drug action may persist for a considerable period.
Formoterol Fumarate is a beta two receptor agonist. They can activate the beta two receptors located within the bronchial smooth muscles. The activation of beta two receptors results in Broncho dilation making it easy for the consumer to breathe. Tiotropium Bromide and Formoterol Fumarate’s combined effect creates an additive effect resulting in better results than when inhaled alone.
Combination brand name agents used to treat COPD are Combivent®, Advair®, Symbicort®, Dulera®, DuoNeb®, BREO® ELLIPTA®, Stiolto® Respimat®, Bevespi® Aerosphere®, Utribron® Neohaler®, and ANORA® ELLPTA®.
Side effects of Duova® Rotacaps
As Duova Rotacaps contains two medications, the consumers may experience both side effects of the medicines. There is a chance to experience hypersensitivity reactions when Duova Rotacaps are used for the very first time. So remember to disclose the allergy history to the physician.
Side effects of Tiotropium Bromide. As Tiotropium Bromide is an anticholinergic medication, the side effects are significantly related to the parasympathetic nervous system. As the function of the parasympathetic nervous system gets altered, the consumer may experience dryness in the oral cavity, Blurred vision, tachycardia, urinary retention, and constipation due to slow bowel movements.
Side effects of Formoterol Fumarate. Like other Beta two agonists, Formoterol Fumarate also exhibits similar side effects. Tachycardia, headache, tremors, muscle cramps, palpitations, the feeling of fatigue, and insomnia are a few common side effects experienced after the use of anticholinergic drugs.
How to use Duova® Rotacaps
Nuova Rotacaps are only indicated to use as an inhaler. Never swallow the Rotacaps. Keep the Rotacaps within the Rotahaler and rotate until you hear the sound to confirm that it is correctly placed. Seal the mouthpiece within the lips and inhale the powdered medication. Inhale several times until you feel all the mediation is taken. Finally, gargle the mouth and throat with water or brush the teeth after inhalation.
- Check for allergic reactions when using Duova Rotacaps for the very first time. If any response is noticed, take medical help immediately.
- If any chance, of bronchospasm, and breathing difficulties are reported, take immediate action to stop the use of Duova Rotacaps and seek medical help.
- Be cautious if you are suffering from glaucoma.
- There is a chance of worse urinary retention. If you suffer from prostate gland issues, urinary retention, or any associated condition, remember to be alert regarding the early signs of urinary retention.
- Be cautious if you have asthma. Discuss with the physician to get advice.
- The reproductive toxicity of Tiotropium Bromide and Formoterol Fumarate is unknown. Therefore instruct your physician if you get pregnant or wish to become pregnant.
- Avoid using Duova Rotacaps during labor, as anticholinergic effects can obstruct the normal labor process.
- Discuss with the physician if you are a lactating mother.
- Avoid using Duova Rotacaps if you are below 18years old.