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Autolyse® Papain + Urea Ointment

Papain 521,700 units/g + Urea 100mg Enzymatic Debriding Agent

(1 customer review)

USD $16.00

Autolyse® Ointment is used to remove dead tissue and thin the pus in lesions such as ulcers, burns, bedsores, surgical wounds, cysts, and carbuncles. Papain is a substance from the papaya fruit. Papain and Urea break down certain proteins.

Autolyse® Ointment contains Papain and Urea. Papain urea ointment is an enzymatic debriding agent. It works by helping the breakdown of dead skin and pus, which helps improve the recovery time of open wounds.

Topical debriding agents are chemicals that are used locally to clean an open wound by removing foreign material and dead tissue so that the wound heals without increased risk of infection. This makes the healing faster.

Size: 15g / 0.53oz
Brand name: Accuzyme, AllanEnzyme, Ethezyme, Gladase, Kovia, Pap-Urea, Paptase
Title Range Discount
Items: 2 - 4 5%
Items: 5 - 8 10%
Items: 9 + 15%


What is Papain + Urea 100mg Autolyse® Ointment?

Autolyse® Ointment is an alternative/substitute/generic to Accuzyme® (papain and urea ointment) enzymatic debriding ointment is used to break down dead skin or tissues in wounds such as bed sores, ulcers, burns, surgical wounds, cysts, and carbuncles. Common side effects of Accuzyme include mild stinging or burning of the skin or skin irritation where the medicine is applied. Tell your doctor if you experience side effects of a severe allergic reaction to Autolyse® Ointment including rash, hives, itching, difficulty breathing, or swelling.

Apply a dose of Autolyse® Ointment directly to the wound, cover with an appropriate dressing, secure it into place. Daily or twice daily applications are preferred. Autolyse® Ointment may interact with hydrogen peroxide applied to the wound area. Tell your doctor all medications and supplements you use. It is unknown if Autolyse® Ointment will be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

One of the main ingredients of the Autolyse® Ointment is Papain in a 521,700 units/g strength. Papain is a protein-cleaving enzyme derived from the papaya fruit (Carica papaya) and certain other plants. Topical drug products containing papain are used for the removal of dead or contaminated tissue in acute and chronic lesions, such as diabetic ulcers, pressure ulcers, varicose ulcers, and traumatic infected wounds. These products combine papain with other active ingredients, such as urea, chlorophyllin copper complex, and copper sodium chlorophyllin, which are intended to promote the removal of unhealthy skin tissue, control local inflammation, reduce wound odors and rehydrate skin.

Side effects of any Papain Urea Ointment | Accuzyme generic

Autolyse® (papain and urea) Ointment is generally well-tolerated and non-irritating. A transient “burning” sensation may be experienced by a small percentage of patients upon applying Autolyse® (papain and urea) Ointment. Occasionally, the profuse exudate from enzymatic digestion may irritate the skin. In such cases, more frequent dressing changes will alleviate discomfort until exudate decreases.

How to use Papain Urea Ointment | Accuzyme generic?

  • Wash your hands before and after applying papain-urea topical.
  • Clean the wound as directed by your doctor. Use only the type of cleanser your doctor has recommended.
  • Apply papain-urea topical directly to the wound. Then cover the treated area with bandaging or other dressing recommended by your doctor. Keep the wound covered at all times, because this medication will cause the dead tissues to slough and peel off.
  • Avoid using hydrogen peroxide to clean your wound before applying papain-urea topical. Hydrogen peroxide can make the papain-urea less effective in breaking down the tissues of your wound.
  • Do not use other medicated skin products unless your doctor has told you to.


  • Papain IP 521700 units of activity
  • Urea IP 100mg