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Tri-Luma cream buy

Where to Buy Tri-Luma Cream Online

If you’re looking for a way to get rid of dark spots, melasma, or hyperpigmentation on your skin, you might have heard of Tri-Luma cream.

Tri-Luma is a prescription-only topical medication that combines three active ingredients to lighten and even out your skin tone. But is Tri-Luma really effective? And where can you buy it online safely and affordably?

In this blog post, we’ll answer these questions and more. We’ll also share some user reviews and experiences with Tri-Luma cream, as well as some tips on how to save money and get the best results. Read on to find out everything you need to know about Tri-Luma cream!

Understanding Tri-Luma Cream

Tri-Luma cream is a product approved by the FDA in 2002 for the treatment of moderate to severe melasma of the face. Melasma is a common skin condition that causes brown or gray patches on the forehead, cheeks, nose, chin, or upper lip.

It’s more common in women than men, and it’s often triggered by hormonal changes, sun exposure, or genetic factors.

But Tri-Luma is not only for melasma. It can also help with other types of hyperpigmentation, such as age spots, sun spots, acne scars, or post-inflammatory marks. Hyperpigmentation is when some areas of your skin produce more melanin than others, resulting in uneven coloration.

This can affect your self-esteem and confidence, especially if it’s on your face.

So how does Tri-Luma work? And what’s inside it? Let’s take a closer look.

What’s Inside Tri-Luma?

Tri-Luma combines three active ingredients, each playing a crucial role in its efficacy:

Hydroquinone (4%):

  • Hydroquinone is the star player in Tri-Luma. As a skin depigmenting agent, it inhibits the production of melanin—the pigment responsible for skin color.
  • By targeting hyperpigmented areas, hydroquinone gradually lightens dark spots, melasma patches, and post-inflammatory pigmentation.
  • Its effectiveness lies in its ability to disrupt the enzymatic processes involved in melanin synthesis.

Tretinoin (0.05%):

  • Tretinoin, a synthetic form of Vitamin A, is renowned for its skin-rejuvenating properties.
  • It stimulates collagen production, accelerates cell turnover, and promotes smoother, firmer skin.
  • When combined with hydroquinone, tretinoin enhances the overall effectiveness of Tri-Luma.

Fluocinolone Acetonide (0.01%):

  • This medium-potency anti-inflammatory agent soothes irritated skin.
  • By minimizing inflammation, it ensures that the skin responds positively to the other active ingredients.
  • Fluocinolone acetonide also prevents systemic effects, making Tri-Luma safe for topical use.

Product application guide

Tri-Luma cream is meant to be used once a day at night before going to bed. You should apply a thin layer of the cream to the affected areas of your face, avoiding the eyes, mouth, nose, and mucous membranes. You should also avoid applying it to irritated or broken skin.

You may use Tri-Luma cream for up to eight weeks or as directed by your doctor. You should not use it longer than prescribed, as this may increase the risk of side effects or resistance.

You should also avoid sun exposure while using Tri-Luma cream, as this may worsen your condition or cause unwanted reactions. You should always wear sunscreen with at least SPF 30 during the day and cover up with protective clothing and hats.

When will I start seeing results?

You should start seeing results within two to four weeks of using Tri-Luma cream. However, this may vary depending on your skin type, severity of your condition, and adherence to the treatment regimen. Some people may see results sooner than others, while some may need more time to achieve their desired outcome.

Note: You should not expect Tri-Luma cream to completely erase your hyperpigmentation or melasma. Rather, you should aim for a significant improvement in your appearance and satisfaction with your skin tone.

You should also keep in mind that Tri-Luma cream is not a permanent solution for your condition. You may need to repeat the treatment periodically or use maintenance therapy to prevent recurrence.

Online Purchase Options

If you’re interested in trying Tri-Luma cream for your skin condition, you might be wondering where you can buy Tri-Luma online. After all, buying online can save you time, money, and hassle compared to going to a physical pharmacy or clinic.

However, not all online sources are reliable or trustworthy. You need to be careful where you shop and what you buy, especially when it comes to prescription medications like Tri-Luma cream.


One of the best places to buy Tri-Luma cream online is Okdermo is an online skin care store that offers a wide range of products for various skin conditions and concerns. Whether you’re looking for acne treatments, anti-aging products, hair loss solutions, or skin-lightening creams, okdermo has it all.

Buy ‘’Tri-Luma Cream for hyperpigmentation’’ here

Tri-Luma Cream reviews

Here are some screenshots we captured from our product page that contain valuable reviews by Tri-Luma users who loved their purchase on Okdermo.

Tri Luma Cream Reviews Tri Luma Cream Reviews Tri Luma Cream Reviews Tri Luma Cream Reviews

Tri-Luma FAQs

  1. Can I buy Tri-Luma over the counter?

Tri-Luma is a prescription medication in some countries, but via okdermo can be purchased over the counter. Generally, you will need a prescription from a healthcare provider to obtain Tri-Luma but OKDERMO has an option to buy Tri-Luma OTC.

  1. How much is Tri-Luma at CVS?

The cost of Tri-Luma can vary depending on factors such as your location, insurance coverage, and the specific formulation. It is recommended to check with your local CVS pharmacy for the most accurate and up-to-date pricing information.

  1. What is equivalent to Tri-Luma?

Other prescription topical treatments for hyperpigmentation and melasma may be considered as alternatives to Tri-Luma. Your healthcare provider can suggest suitable alternatives based on your specific skin condition and needs.

  1. How much does Tri-Luma cost?

The cost of Tri-Luma can vary depending on where you purchase them from and, currently, it sells for 40$ on our site (15g). To get the most accurate pricing information, it’s advisable to check it with our product page or your local pharmacy.

  1. Is Tri-Luma worth the money?

The short answer is ‘’Yes’’. It is an effective medication designed to treat certain skin conditions, and its use should be guided by a healthcare professional. Discuss the potential benefits and risks with your doctor to determine if Tri-Luma is the right option for you.

  1. Is there a generic Tri-Luma?

As of now, there are some generic versions of Tri-Luma available.

  1. Does melasma come back after Tri-Luma?

Melasma is a chronic skin condition, and while Tri-Luma can be effective in treating it, there is a possibility of recurrence. The likelihood of melasma returning after treatment with Tri-Luma can vary among individuals.

     8. Where to buy Tri-Luma cream online?

You can always purchase Tri-Luma online over the counter via the OKDERMO Skincare Store. Highest quality and best prices guaranteed.


In conclusion, Tri-Luma cream stands as an FDA-approved solution for treating moderate to severe melasma and various forms of hyperpigmentation. With its powerful trio of active ingredients—Hydroquinone, Tretinoin, and Fluocinolone Acetonide—it targets melanin production, promotes skin rejuvenation, and soothes inflammation.

The proper application of Tri-Luma, as outlined in the product guide, involves nightly use on affected areas, avoiding sensitive regions and prolonged sun exposure. Users can anticipate visible results within two to four weeks, although individual responses may vary.

While Tri-Luma offers notable improvements in skin tone and appearance, it’s essential to recognize that it may not entirely eliminate hyperpigmentation. Periodic treatments or maintenance therapy might be necessary to prevent recurrence.

Post by:

Dermatologist Marcela J






Marcella Jiovanni

Skin Care Professional

“Marcella Jiovanni actively promotes the importance of maintaining healthy skin, she envisions the future of dermatology as moving away from pure medical, pharmacological dermatology and flowing more toward a holistic approach to wellness and skincare.”