Hyde®/Epilite® Topical Solution

Hydroquinone 5% USP

4.15 out of 5

(20 customer reviews)

From USD $26.00 (EUR €21.58)

5 Hydroquinone USP topical liquid solution by reputable brand Menarini consist of high-quality Hydroquinone monohydrate 5% which is used flawlessly in dermatology for flawless skin hyperpigmentation treatment, dark skin patches, melasma, and other skin discolorations. Hydroquinone 5% is an ingredient found in many skin-lightening products marketed to women for purposes of reducing age spots, melasma, freckles, and other types of hyperpigmentation. Depending on the concentration of hydroquinone in your skin lightener, you may get sufficient results.


  • Melasma, freckles, chloasma, senile lentigines
  • Sun-induced pigmentation
  • Post-inflammatory hyperpigmentation
Brand name: Mediquin, Vitaquin, Interquin
Items:2 - 4 5%
Items:5 - 8 10%
Items:9 + 15%


What is Hydroquinone 5 USP Skin Liquid Solution

HQ 5% solution with maximum strength Hydroquinone five percent is the gold standard option for chemical treating of hyperpigmentary disorders. Hydroquinone 5% blocks melanin synthesis and evens out skin tone, generally prescribed to brighten dark spots on the skin caused by pregnancy, birth control pills, hormonal therapy, or skin lesions. HQ 5% Skin Solution is a pH-adjusted lotion form formulation with excellent stability, good spreadability, and lesser side effects hence increase patient compliance. Always consult your dermatologist prior to using strong topical skin lighteners, especially containing hydroquinone as an active ingredient.

Hydroquinone 5 liquid topical solution USP by reputable brand Menarini consist of high-quality Hydroquinone monohydrate 5 which is used flawlessly in dermatology for skin hyperpigmentation treatment, dark skin patches, melasma, and other skin discolorations. Hydroquinone 5 is an ingredient found in many skin-lightening products marketed to women for purposes of reducing age spots, melasma, freckles, and other types of hyperpigmentation. Depending on the concentration of hydroquinone in your skin lightener, you may get sufficient results; however, there are known side effects you should be aware of when using a hydroquinone-based lightening solution.

The term skin hyperpigmentation refers to the dark, discolored patches of skin that occur when melanin is overproduced. Reasons for this overproduction include sun exposure, skin damage, hormones, and certain medications. The condition is typically harmless, though its appearance on prominent areas of the body – such as the face, can affect your self-esteem. Fortunately, there are several fade creams like 5 Hydroquinone Solution intended for melasma recovery. Consult a professional dermatologist to determine one that is suitable for you.

When used in skin-lightening creams and similar products, hydroquinone 5% inhibits the production of melanin, the pigment that gives your skin its color. Cosmetic skin-lightening products containing hydroquinone often have a strident scent reminiscent of bleach, and in fact, they are often referred to as “bleaching creams.”

Skin irritation: A common effect associated with hydroquinone 5 is skin irritation. It should not be used on skin that is dry, chapped, sunburned, or already irritated, nor should it be applied to an open wound. Irritation can be reduced by avoiding the use of harsh cleaning agents, such as soaps and shampoos, hair dye, permanent waves, cream depilatories, waxes made for hair removal, and products that contain alcohol, lime, spices, or other astringents. Avoid using medicated products unless instructed by a dermatologist.

Sun sensitivity: Hydroquinone 5% makes your skin more sensitive to the sun’s damaging ultraviolet rays. However, if you are trying to fade sun spots, freckles, and other types of hyperpigmentation, sun protection is essential, as sun exposure in itself makes discoloration worse. Always smooth on a broad-spectrum sunscreen before you go outdoors so you will not undo the benefits of your skin-lightening products.

Cautions: If purchasing a skin-lightening cream that contains hydroquinone 5%, make sure to read the product’s label first. If you use a topical cream that contains too much hydroquinone you might end up with discoloration that is almost impossible to treat. Only your dermatologist can tell you if it is safe to use hydroquinone 5% at a concentration of more than two percent.

HQ 5% Topical Solution is used in the treatment of melasma. It is a skin-lightening medicine that lightens the darkened skin patches and spots (hyperpigmentation). It reduces the amount of skin-darkening pigment called melanin in the skin. It helps in reversible depigmentation of the skin. HQ 5%  Topical Solution is for external use only. You should use it in the dose and duration as advised by your dermatologist and under medical supervision. You must wash your hands thoroughly before and after applying for this medicine. This medicine should be used regularly to get the most benefit from it. Do not use more than you need as some side effects may be increased. Do not use longer than 4 months in a row, interchange HQ 5% with some natural skin lighteners like Arbutin or Azelaic Acid.

HQ 5% Topical Solution has a few potential side effects but not everyone will get them. These may include dry skin, itching, skin burn, skin peeling, and skin redness. Serious allergic reaction to this drug is rare but let your doctor know if you’re bothered by side effects or they do not go away. Make sure you read the instructions that come with your medicine. Avoid contact with eyes. In case of accidental contact, you should rinse your eyes thoroughly with water. You can start applying HQ 5% Topical Solution to a small portion of unbroken skin or near the pigmented area for a period of several days for checking allergic reactions. You should discontinue it if itching, excessive inflammation, or swelling occurs. If no improvement is seen after two months of treatment, the use of this product should be discontinued.

Pregnant, becoming pregnant or breastfeeding women should not use this product or only after their doctor consultation.

5 Hydroquinone USP Liquid Solution Benefits

5% Hydroquinone USP Topical Solution designed to lighten discolorations in the skin. It works by reducing the amount of melanin in the skin, making darkened areas lighter. Consumers are buying hydroquinone 5% of products for their convenience and results.

USP Topical Solution contains hydroquinone 5% a chemical that is used as a skin lightener to reduce the color of the highly pigmented skin due to overproduction of the pigment melanin, in a variety of skin conditions. Hydroquinone 5% of  Topical Solution works by Inhibiting tyrosinase, an enzyme involved in the production of melanin, which is the pigment that gives color to the skin. This slows down the production of melanin, so that as the amount of melanin decreases the darkened skin gradually fades to match the normal skin. The skin conditions that  Solution is effective in treating include, liver spots or age spots, also known as senile lentigines, that are common in aging skin, freckles, acne scars, and other forms of unwanted skin discoloration. HQ 5%  Topical Solution is also used to treat melasma, which are patches of dark skin discoloration that appear in areas of the face and are caused by exposure to the sun, pregnancy, and contraceptive hormones.

Easy to apply: Hydroquinone 5 USP Skin Solution is painless and easy to apply during your regular morning routine. Manufacturers recommend that the cream is applied regularly, usually once a day, to the discolored areas of skin and rubbed in thoroughly. This ensures that the component is applied only to the areas that need treatment.

Quick results: Most users who use HQ 5% Hydroquinone USP Topical Solution see a change in the discolored skin within three weeks when using the cream twice a day or once a day. Although the cream may take longer to work in some users, its effectiveness can usually be determined within four months. Alternative methods of treating skin discoloration, such as dermabrasion, require scheduled treatments and a healing period of several days or weeks, which Hydroquinone 5% USP Solution does not require.

How does 5% Hydroquinone Liquid Topical Solution work

Hydroquinone 5% Solution belongs to components called melanin synthesis inhibitors. It bleaches, whitens the skin by removing the accumulated skin pigment called melanin that causes darkening of skin areas. Some side effects may appear – allergic to any component of cream, irritation.

Contraindications of 5% Hydroquinone Topical Solution

  • Pregnancy and lactation
  • Acute inflammation (including eczema) lesions of the skin (dermatitis, seborrhea, and others.)
  • Rosacea, skin lesions (wounds, burns, etc.), photosensitivity
  • Diseases of the rectum, of liver or kidney, Addison’s disease
  • Asthma, allergic to sulfites, or to any of the components of the cream
  • Hypersensitivity to any component of the cream (discontinue use and consult a doctor if you have any of these symptoms of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat).

Related resources/references:

  1. FAQ hydroquinone topical cream
  2. How to use hydroquinone HQ cream
  3. What is melasma and hyperpigmentation
  4. About hydroquinone topical
  5. Hydroquinone topical side effects
  6. Hydroquinone cream during pregnancy
  7. Hydroquinone with sunscreen

Additional Information

20 reviews for Hyde®/Epilite® Topical Solution

  1. 4 out of 5

    Willie D.

    Hydroquinone works, and can be used to treat not only dark spots but also freckles and scars. Helped me, was prescribed me by the doctor.

  2. 5 out of 5

    Jane Terry

    I’ve heard liquid hydroquinone is more effective than a cream form because it penetrates better.

  3. 4 out of 5

    Tiffany W.

    It’s highly effective and also works faster than other products on the market! Delivery and order process quite annoying

  4. 4 out of 5

    Melvin P.

    Delivered but glass bottle was broken, been reshipped. Received in 3 weeks.

  5. 5 out of 5

    Cornelius C.

    I use hydroquinone lotion in conjunction with other skin brightening ingredients such as Vitamin C, Glycolic Acid and Retin-A for a multi-prong approach, my acne scars and dark spots gone, now using onlysun avoidance program and keep apply organic skin lighteners. Like the results I got!

  6. 5 out of 5

    June Hawkins

    It works, simply works on me! Very happy that my doctor recommended it! Diluted with cocoa butter and apply every night, USE SUNSCREEN SPF 100 always with it!

  7. 2 out of 5

    Raymond Norman

    It burned my skin and i had to go a derm!

  8. 4 out of 5

    Linda Harrington

    Which one is better – cream or solution?

  9. 5 out of 5

    Brooke P

    This HQ lotion is highly effective, and works by blocking a melanin-producing enzyme called tyrosinase as my doctor said, my dark hypopigmentation faded, almost one tone to my skin, thanx for a great product. Use with caution.

  10. 5 out of 5


    Arrived undamaged, that’s good, 5% is pretty high concentreation, i like it strength!

  11. 3 out of 5

    Stacy Huff

    The skin fading effects lasts as long as you use the product so exposure to the sun can trigger more pigment production and the return of the dark spot.

  12. 5 out of 5

    Krystal Rogers

    All types of Hydroquinone work the same if you have constant use. I personally like combining HQ treatments with other lightening creams (more natural ones like azelaic acid, glycolic acid, kojic acid etc) that not only stop the product of pigment but work to remove pigment and prevent any further pigmentation.

  13. 5 out of 5

    Kerry C

    Received mine today, thank you!

  14. 4 out of 5

    Angie A

    It essentially bleaches the skin, my chloasma almost gone on 3rd week of treatment.

  15. 4 out of 5

    Cristina Parks

    Do you recommend liquid over cream form?

  16. 4 out of 5

    Kelli M.

    Works to fade dark spots and discoloration

  17. 5 out of 5

    Edgar King

    Yes, love this lotion, I can mix it with anything, with my fav moisturizer for example.

  18. 2 out of 5

    Katrina Lee

    Lotion caused excessively dry skin, as well as redness and a burning sensation. Will continue to use a cream better.

  19. 3 out of 5


    Anyone using a prescription strength product should be closely monitored by their doctor. Some dermatologists simply won’t prescribe it as they feel the risks outweigh the benefits, and feel that other potentially safer products can achieve similar results, like Rucinol, Kojic Acid, Azelaic Acid 20%, and other natural solutions.

  20. 5 out of 5

    Zephyr (verified owner)

    I find this easier to apply than cream-based alternatives, given that you transfer it to a pump bottle first (be sure to cover it with aluminum foil to avoid photo-degradation). The downside is that you’ll end up using it up a lot faster than creams.

Add a review

Your email address will not be published. Required fields are marked *