A Ret-HC® Cream 15g/0.53oz

Hydroquinone 2% + Tretinoin 0.05% + Hydrocortisone Acetate 1%

3.95 out of 5

(28 customer reviews)

USD $24.50


A Ret-HC cream from a reputable Menarini company is a triple combination type of skin cream with the following ingredients list: hydroquinone, tretinoin, and hydrocortisone acetate.

The cream can be used for the gradual bleaching of hyperpigmented skin conditions. A Ret-HC cream is used to treat skin darkening conditions such as freckles, melasma, hyperpigmentations, age spots, and even scars caused by acne.

A-Ret HC cream should be used as directed by a dermatologist within the total sun avoidance program.

Items:3 - 5 5%
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A Ret-HC cream from reputable Menarini Pharma is a triple combination type of medical-grade ingredients containing hydroquinone, tretinoin, and hydrocortisone acetate. The cream can be used for the gradual bleaching of hyperpigmented skin conditions. A Ret-HC cream is used to treat skin darkening conditions such as freckles, melasma, hyperpigmentations, age spots, and even scars caused by acne.

Hydroquinone 2% – bleaches the skin by reducing the accumulation of skin pigment called melanin that causes darkening of the skin. It interferes with the synthesis of melanin and hampers important processes within cells that produce melanin (melanocytes). The bleaching effect of hydroquinone is reversible (reversible depigmentation) with sun exposure. So it should be used within a total sun avoidance program.

Tretinoin 0.05% – topical vitamin A derivative, exfoliant, skin oil sebum glands inhibitor, works by slowing the production of certain natural substances that can cause acne.

Hydrocortisone Acetate 1% – is a topical anti-inflammatory agent. It works by reducing redness, itching, and swelling caused by various skin conditions.


A Ret-HC cream with hydroquinone 2 percent, tretinoin 0.05 percent, and hydrocortisone acetate 1 percent should be applied topically to the affected area once daily in the evening or as otherwise directed by a dermatologist. Contact your dermatologist for the correct dosage and length of treatment as it will depend on condition and skin response. Prior to applying this medicated cream, wash and dry your hands and the affected area with water. Apply a small amount of the cream to the affected area and gently massage it into the skin until it disappears.

A Ret-HC cream users may encounter unwanted side effects such as dry skin, erythema, stinging, irritation, itching or burning at the application site, hypersensitivity to light, hair thinning. Seek medical advice immediately if side effects persist or worsen. Only apply for the treatment of acne scars and for skin depigmenting. Immediately proceed to your nearest emergency department if you suffer an allergic reaction. Symptoms usually associated with such a reaction include difficulty breathing or swallowing, chest tightness, swelling, skin rashes, and hives.

A Ret-HC cream with hydroquinone 2%, tretinoin 0.05%, and hydrocortisone acetate 1% is not always suitable for all users. Always consult your dermatologist prior to using this cream if you are pregnant, breastfeeding, trying to conceive, using any other medication, using any herbal products or supplements, or if you have any allergies or other health problems. The correct dosage and prescription commonly depend on the patient and the condition being treated. Do not adjust your dosage without the approval of your healthcare provider. This product is only for use as prescribed and instructed.

Related resources/references:

  1. FAQ hydroquinone topical cream
  2. How to use hydroquinone HQ cream
  3. What is melasma and hyperpigmentation
  4. About hydroquinone topical
  5. Hydroquinone topical side effects
  6. Hydroquinone cream during pregnancy
  7. Hydroquinone with sunscreen

Brand names: Aclaro, Alera, Alphaquin HP, Eldopaque, Eldoquin, EpiQuin Micro, Esoterica Daytime, Hydroquinone and Sunscreen, Lustra, Melpaque HP, Melquin HP, Nuquin HP, Palmers Skin Success Eventone Fade, Remergent HQ



The Menarini Group is an Italian pharmaceutical company. Its headquarters is in Florence and has three divisions: Menarini Ricerche, Menarini Biotech and Menarini Diagnostics. It is committed to the search for pharmacological solutions for such therapeutic areas as cardiovascular diseases, oncology, pain/inflammation, asthma, and anti-infectives. Menarini's research activities are carried out through Menarini Ricerche, which deals with all R&D activities, from the creation of new projects up to the drug registration. Its Menarini Biotech follows the creation of a biotechnological drug from the very early stages of research, through to the pilot scale and up to industrial production. The Group's Menarini Diagnostics division is a health care company with a worldwide network of affiliates partners and distributors focused on diabetes, hematology, clinical chemistry, urinalysis, and immunology. In 2011, the company had 13,081 employees worldwide. Menarini India is the Indian affiliate of the Menarini Group, which is a leading biopharmaceutical company, focused on delivering differentiated ethical and consumer healthcare brands across the world. A. Menarini India operates across the entire commercial value chain, from regulatory approval and product launch to lifecycle management and offers an unparalleled customer experience to all stakeholders including partners wanting to tap into the India growth story. Through our team of over 1,200 passionate sales, marketing and support professionals, Menarini India manages a diverse portfolio of proprietary healthcare brands as well as licensed brands from global biotech and multinational companies. Leveraging the strengths of its infrastructure, Menarini India is able to tap onto extensive global resources and its' own unique local customer insights to deliver innovative brands from R&D, through to manufacturing, regulatory approvals, and commercialization. Menarini India operates in one of the fastest growing healthcare markets worldwide, increasing at an annual compounded growth rate of 15%, more than double the global growth rate for the sector. With India being among the top growth contributors globally, Menarini India is establishing itself as a leader in this rapidly expanding market through targeted investments. With over 3,300 professionals in 13 major markets, Menarini Asia-Pacific operates across the entire commercial value chain, from regulatory approval and product launch to lifecycle management and offers an unparalleled customer experience to partners wanting to tap into the Asia-Pacific growth story. To be the leading provider of important healthcare brands that improve the lives of people in the Asia-Pacific region. Menarini India continues to build its reputation as a fully integrated biopharmaceutical company based on the illustrious history and success of the Menarini Group. It operates one of the most effective and experienced professional sales and marketing organizations in the region, while practicing transparency and excellent corporate governance. Our people are our greatest assets. To encourage their best efforts, we treat each of our employees with fairness and respect, providing them with the support needed to achieve their professional goals. We believe the following four key values will be the source of our success:
  • Integrity - we do what we say, and do what is right
  • Customer Focus - we delight our customers by delivering and exceeding their expectations
  • Sense of Urgency - we value speed and despise bureaucracy
  • Ambition - we aspire to stay at the forefront of our industry by setting lofty goals


Hydroquinone 2 %

Tretinoin 0.05 %

Hydrocortisone Acetate 1%

Cream base q.s.

28 reviews for A Ret-HC® Cream 15g/0.53oz

  1. 5 out of 5

    Latricia Jacques

    Very satisfied and happy with the result. As long as you put sunscreen, you’re fine.

  2. 4 out of 5


    I had dark spots on my nose, forehead and chin. I use a cream almost every night for a 1,5 month and spots disappeared. It has been almost 7 years and and I noticed a small spots on my cheek and neck so I am going to try again

  3. 4 out of 5

    Cassey P.

    Even though this is not a cure, in less than ten days my spots are visibly lighter and barely noticeable. It works!

  4. 5 out of 5

    Lizbeth S.

    I have used it for 4 nights now and it has faded the splotches significantly!! Wow!

  5. 5 out of 5


    This combination of chemicals works a whole lot better than hydroquinone on its own.

  6. 4 out of 5

    Gretchen T

    The only downside to this cream is that you do have to be VERY careful around the corners of your mouth and open sores.

  7. 3 out of 5


    Better consult with the cosmetologist/dermatologist/doctor prior trying it. It may not suit your skin type

  8. 2 out of 5


    This Cream will only work when you apply it.

  9. 5 out of 5

    Estella Antoine

    Within 2 weeks there was a noticeable difference.

  10. 5 out of 5

    Jada Weinstein

    work in less than a week!

  11. 5 out of 5

    Pansy Houghton

    A Ret-HC works great. Have been using it for post inflammatory hyperpigmentation. Only thing is that just as soon as you stop using it the dark areas come back, BUT I found the way to solve that, try using this cream fro the first 2-3 months and then continue to use only azelaic acid gel 20% and pigment will not return and skin will remail healthy! Bingo! But please use sunscreen always SPF 50

  12. 2 out of 5

    Kittie Oliva

    I started yesterday and today I see it darker. Should I stop?

  13. 5 out of 5


    I absolutely LOVE this product!!

  14. 5 out of 5


    This product is amazing!

  15. 4 out of 5


    I was very sceptical first, but this is a product that TRULY WORKS,

  16. 3 out of 5


    Use it with caution, it is a medicated solution

  17. 5 out of 5

    Merlyn Avery

    By 4 week it had all gone! Thanx okdermo! Wonderful cream!

  18. Truman Pacheco

    Amazing results with an A Ret HC! I’ve struggled with melasma for a long time. And now I’m almost done fightnig with it!

  19. 2 out of 5

    Marth Reilly

    After four months of treatment Melasma got worse. Worseless

  20. 1 out of 5

    Mammie F.

    The brown spot became darker

  21. Elinor

    Some people have commented that their skin actually has gotten darker a few days after beginning to apply A Ret-HC. The same happened to me, but I realized that my problem was that after I applied A Ret-HC before bed time, I would read for about one hour with a light directly on my face. The chemicals in the cream were reacting to the light. I stopped the treatment for a few days. When again I started applying A Ret-HC, I immediately turned off the lights and went to sleep. That worked! After two months I now have about 90% clearer skin (I am olive skinned).

  22. Bebe M.

    It removes any mark from a burn, inflammation, etc in a month or under..its amazing.

  23. Myrtis T.

    I’m so amazed saw a huge difference in 4 days and my cheeks are CLEAR.

  24. Teresa H

    I’m so happy with my results!

  25. Erica L.

    But it definitely works. Very excited to not look like a star trek character anymore 😉

  26. Thomas Brantley

    Everyone WOC needs this in her medicine cabinet.

  27. Jae Mccracken

    It’s hard to believe that there is a product out there that actually works but this is it.

  28. 5 out of 5


    I was prescribed this by my dermatologist because I was developing brownish skin on my upper lip during the summer when I have more sun exposure. On second week of treatment skin was back to normal, I’m pretty surprised!

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