Nailrox® Nail Lacquer 5ml/0.16fl.oz

Ciclopirox Olamine 8% Topical Solution

USD $24.50

Ciclopirox nail lacquer is used to treat fungal infections of the toenails and fingernails.

The good news is that there are treatments that can remove toenail fungus permanently. If you’re looking for a treatment that works, consider something that will tackle the symptoms while killing the fungus at the same time, like Ciclopirox nail lacquer.

Ciclopirox toenail lacquer is one proven way to clear up toenail fungus. It is a no prescription-strength solution but must be advised by a doctor to use it.

TitleRangeDiscount
Items:3 - 5 5%
Items:6 - 9 10%
Items:10 + 15%

Description

Cyclopirox Olamine 1% and 8% Cream Gel Lacquer Liquid Lotion Solution Synpirox, C Win 1%,  Triogel, Pretifungin 1%, Cyclonus, Ciclodan, CNL8, Loprox, Loprox TS, Penlac

Nailrox® Topical Solution Nail Lacquer is manufactured by reputable Intas Pharmaceuticals LTD. Nailrox Ciclopirox Nail Lacquer contains Ciclopirox Olamine USP 8% active salt. This medication is used to treat fungal nail infections such as onychomycosis, also known as tinea unguium, is a fungal infection of the nail. Symptoms may include white or yellow nail discoloration, thickening of the nail, and separation of the nail from the nail bed. Toenails or fingernails may be affected, but it is more common for toenails to be affected. 8% Ciclopirox over the counter is an antifungal agent that works by stopping the growth of fungus. Nairox is an alternative/generic to Penlac nail lacquer over the counter.

Nailrox is an alternative to Loprox nail lacquer over the counter (Ciclopirox nail lacquer) is a topical treatment for fungal infections of the nails, known as onychomycosis, due to dermatophytes like Tinea and molds like Trichophyton that cause common skin infections known as ringworm. These include tinea of the body (tinea pedis), foot (tinea corporis) and groin (tinea cruris); also tinea (pityriasis) versicolor a form of dermatitis due to the dermatophyte Malassezia. Ciclopirox nail lacquer is also effective against candidiasis or thrush of the nail caused by infection with yeasts like Candida albicans.

The symptoms that go along with toenail fungus make life uncomfortable. These include the discoloration and thickening of the toenail, not to mention pain and a nasty odor. The good news is that there are treatments that can remove toenail fungus permanently. If you’re looking for a treatment that works, consider something that will tackle the symptoms while killing the fungus at the same time, like Ciclopirox nail lacquer.

Ciclopirox toenail lacquer is one proven way to clear up toenail fungus. It is a prescription-strength solution that must be advised by a doctor to use it. However, if you have a severe fungal infection, seeking out treatment options from your doctor can sometimes be the better choice.

If you’re struggling with a severe fungal infection of the toenails, it’s important to see a podiatrist and use ciclopirox solution. No one wants a nasty fungal infection. If you’ve tried best over-the-counter toenail fungus treatment options and nothing works, consider this nail lacquer. When used correctly, it’s powerful enough to wipe out any nail fungus. With consistent use, it can clear away the symptoms of an infected nail. This allows you to grow a new, healthy nail that is completely free of infection.

Ciclopirox brand names and generics: Synpirox, C Win 1%,  Triogel, Pretifungin 1%, Cyclonus, Ciclodan, CNL8, Loprox, Loprox TS, Penlac, Pedipirox-4.


How To Use 8% Ciclopirox Nail Lacquer

  • Use on the nails and immediately surrounding skin only. Avoid contact with other areas. Remove any loose nail or nail material using nail clippers or a nail file.
  • Apply Ciclopirox nail lacquer once daily (preferably at bedtime) to all affected nails with the applicator brush provided. Apply the lacquer evenly over the entire nail. Where possible, apply the nail lacquer to the underside of the nail and to the skin beneath it. Allow the lacquer to dry (approximately 30 seconds) before putting on socks or stockings. After applying the medication, wait 8 hours before taking a bath or shower.
  • Apply ciclopirox nail lacquer daily over the previous coat. Once a week, remove the nail lacquer with alcohol. Remove as much as possible of the damaged nail using nail clippers or nail a file.
  • To prevent the screw cap from sticking to the bottle, do not allow the solution to get into the bottle treads. To prevent the solution from drying out, close the bottle tightly after every use.

Treatment with ciclopirox nail lacquer may require several months before initial improvement of symptoms is noticed. Up to 48 weeks of daily application of the nail lacquer, monthly removal of the unattached infected nail by a health care professional, and weekly trimming by the patient may be required for complete treatment.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antifungal medicine.

You have to apply Ciclopirox nail lacquer using the applicator brush provided, after first removing any loose nail or pieces with nail clippers or a nail file. Apply to all the affected nails preferably at bedtime, and allow the lacquer to dry fully before putting on socks; wait 8 hours before showering or bathing. Apply every other day for one month then twice per week for four weeks, then once per week for another month. If the infection has not cleared up, start the treatment again. Initially, apply the next coat over the previous coat then once a week (every 7 days) remove the nail lacquer using a commercial nail polish remover before applying a fresh coat; continue to remove areas of the damaged nail.

It usually takes 48 weeks before the infection has cleared up and it may take up to 6 months before any signs of improvement are seen. Keep away from the eyes and genital area, as it is an irritant and do not take orally, it is only intended for topical application. Do not apply a commercial nail varnish while using Ciclopirox.

You should continue to apply Ciclopirox nail lacquer until the infection has cleared up, or as long as recommended by your doctor, which may take up to 6 months.


Mechanism of Action of Ciclopirox Topical Solution 8 Percent

Nailrox Ciclopirox nail lacquer contains ciclopirox, a broad spectrum antifungal that is used in solution as a topical application for treatment of onychomycosis or fungal infection of the nails. Unlike other antifungals, Ciclopirox in Nailrox nail lacquer does not have any effect on the fungal cell membrane or its integrity. Instead, Ciclopirox in Nailrox works mainly by binding to (chelating) metal ions (Fe3+ or Al3+) and inhibiting metal-dependent enzymes that are responsible for the degradation of peroxides, which protect cells against oxidative damage. Ciclopirox is also thought to cause disruption of the intracellular processes like DNA repair, cell division, and intracellular transport. Ciclopirox is fungistatic (prevents fungal cell growth) and fungicidal (kills the fungus) against a wide range of fungi and yeast, including tinea pedis, tinea cruris and tinea corporis due to Trichophyton rubrum, trichophyton mentagrophytes, epidermophyton floccosum and microsporumcanis.


What Does Neilrox Contain?

Ciclopirox nail lacquer is a topical solution that contains the active ingredient ciclopirox 8%w/w (80mg ciclopirox/m nail varnish). It also contains monobutyl ester of poly (methyl vinyl ether/maleic acid) in isopropyl alcohol, isoprophyl alcohol USP, ethyl acetate NF.


Treating fungal infections of the nails with Ciclopirox

Nailrox Ciclopirox nail lacquer contains ciclopirox, a broad spectrum antifungal that is used in solution as a topical application for treatment of onychomycosis or fungal infection of the nails. Ciclopirox nail lacquer is effective against several fungi that cause common skin infections such as tinea, also known as ringworm and candidiasis or thrush of the nail caused by infection with yeasts like Candida albicans. Ciclopirox nail lacquer works by preventing fungal cell growth and killing the fungus by mechanisms that include disruption of several intracellular processes.


What are the side effects of Ciclopirox?

The most commonly reported side effects when taking Apo- Ciclopirox includes skin irritation, redness or rash around the application area.


When should Ciclopirox not be used?

You should not use Ciclopirox if you:

  • are allergic to ciclopirox or any ingredients in Apo-Ciclopirox
  • are pregnant or are breastfeeding
  • have diabetic neuropathy with numbness in your toes or fingers without discussion with your doctor

Brand

Intas Pharmaceuticals

The Biologics Business Unit (BU) of Intas Pharmaceuticals Limited was formerly an independent biotechnology company and was known as Intas Biopharmaceuticals Ltd. Intas Pharmaceuticals Limited is an Indian company headquartered in Ahmedabad, India. The Biologics BU is located in Moraiya, Ahmedabad and is one of the leading biosimilar product manufacturers in Asia. Intas is a leading, vertically integrated global pharmaceutical formulation development, manufacturing, and marketing company headquartered in India. Intas' success and incessant growth lies in clinical execution of successful and strategic moves made in the areas of manufacturing, R&D, Biotechnology and global operations over three decades. As on 31st of March 2018, Intas has recorded a global turnover of $1.7 billion at >20% CAGR over the last 5 years. Intas is currently ranked 11th in the Indian Pharma Market with 2.9% market share*. In the domestic market, Intas enjoys a leadership position in chronic therapies such as Neurology, Psychiatry, Cardiovascular, Diabetes, Oncology, Urology, Nephrology, Rheumatology & Gynecology, Infertility, Gastroenterology, Pain Management and healthy presence in other major therapeutic segments. Besides well-established domestic prominence, Intas is also present in more than 80 countries worldwide with robust sales, marketing and distribution infrastructure in markets like North America, Europe, Central & Latin America, Africa, Australia, New Zealand, Asia-Pacific as well as CIS and MENA countries. Intas' global strategy includes alliances with leading Global Pharma Companies for the development and distribution of products as well as direct product distribution. The company is known for its range of products in Oncology and other hospital-based therapeutic segments in the EU and US. After the landmark acquisition of Teva's assets, Intas has become a leading player in the generics market in the UK. Intas' success and growth is a direct influence of Intas' extensive R&D capabilities, its manufacturing abilities, and its people. Every year, the company invests around 6-7% of its revenues in R&D. Besides building the regular portfolio of generic products, Intas' R&D is also focused on creating a pipeline of novel drug delivery technology-based products and biologics and has invested over $125 million to develop and enhance its biosimilar capabilities over the past 8 years. Intas operates fourteen formulation manufacturing facilities, of which seven are located in India, and the rest in the U.K. and Mexico. Two of their flagship facilities are accredited by top global regulators such as USFDA, EMA, MHRA, TGA, etc. It is also the first company in India to have its biologics manufacturing facility accredited by the European Health Authority. Intas operates sixteen formulation manufacturing facilities, of which eleven are located in India, and the rest in the U.K. and Mexico. It also operates two API and intermediate manufacturing facilities, each of which complies with the regulatory requirements in the jurisdictions in which it operates. Between them, these facilities have received approvals from various prominent international regulatory bodies, including from U.S. Food and Drug Administration (FDA). Each of Intas' manufacturing facilities is designed, equipped and operated to deliver high-quality products within defined cost and delivery schedules. These manufacturing facilities have the flexibility to operate in various dosage forms and a wide range of batch sizes. Intas' world class oncology formulation facility operates under global regulatory and safety standards. The Ahmedabad SEZ caters exclusively to the US, Europe and other regulated markets. A highly advanced upcoming facility in Ahmedabad, Gujarat is set to double Intas' manufacturing capabilities.

Composition

Ciclopirox Olamine (8% w/v)

Solution Lacquer q.s.

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