What is Candiface® Itraconazole 100mg/200mg Capsules
Itraconazole (Candiface 100/200) 100mg and 200mg capsule is a triazole antifungal agent used to treat various fungal infections. This medicine may also be used to prevent fungal infections if you have a weak immune system due to viral or blood diseases. Itraconazole is a triazole derivative antifungal agent that inhibits the activity of fungal CYP450, thereby decreasing the biosynthesis of ergosterol and inhibiting the formation of the fungal cell membrane.
Candiface Capsule belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat infections of the mouth, throat, vagina, and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane. Candiface is used to treat infections in different parts of the body caused by fungi. It works by killing and stopping the growth of fungi. This provides relief from various symptoms caused by the infection and speeds up the healing process. You should keep taking the medicine until you complete the dose even if you get better. This will prevent the infection from returning.
Itraconazole is available in several different forms. Oral itraconazole is used to treat fungal infections in the lungs, fingernails, and toenails. Itraconazole oral solution is used to treat oral thrush.
Side effects of itraconazole include headache, dizziness, upset stomach, abdominal pain, diarrhea, unusual or unpleasant taste in your mouth, and itching or skin rash.
How to treat fungus with the Candiface® Itraconazole Capsules
- Adult: Esophageal candidiasis; Oral candidiasis: As an oral solution: 200 mg daily, preferably in 2 divided doses or as a single daily dose for 1-2 weeks.
- For fluconazole-resistant infection: 100-200 mg twice a day for 2-4 weeks.
- Prevention of fungal infections in immunocompromised patients: As an oral solution: 5 mg/kg daily in 2 divided doses.
- Oropharyngeal candidiasis: As cap: 100 mg once daily for 15 days.
- In patients with AIDS or neutropenia: 200 mg once daily for 15 days.
- Vulvovaginal candidiasis: As cap: 200 mg twice a day for one day.
- Pityriasis Versicolor: As cap: 200 mg once daily for seven days.
- Tinea corporis; Tinea cruris: As cap: 100 mg once daily for 15 days or 200 mg once daily for seven days.
- Tinea manuum; Tinea pedis: As cap: 100 mg once daily for 30 days. As pulse treatment: 200 mg twice a day for seven days.
- Nail fungal infections: As cap: 200 mg once daily for 90 days. As pulse treatment: 200 mg twice a day for seven days, repeated once for fingernails and twice for toenails after drug-free intervals of 21 days.
- Systemic fungal infections: As cap: 100-200 mg once daily, may increase to 200 mg twice a day for invasive or disseminated infections. In life-threatening diseases: As cap: Loading dose: 200 mg three times a day for three days.
- Prevention of Infections in neutropenic or AIDS patients: As cap: 200 mg daily, may increase to 200 mg twice a day if necessary.
Contraindications of Candiface® Itraconazole Capsules
People with the following medical conditions should not take Itraconazole:
- Non-life-threatening indications in patients with ventricular dysfunction (e.g., congestive heart failure (CHF), history of CHF)
- Severe renal impairment (IV)
- Pregnancy (non-life-threatening infection)
- Coadministration with astemizole, bepridil, cisapride, disopyramide, dofetilide, dronedarone, eplerenone, ergot alkaloids, felodipine, halofantrine, irinotecan, ivabradine, lercanidipine, levacetylmethadol, lovastatin, lurasidone, methadone, midazolam (oral), misolaztine, nisoldipine, pimozide, quinidine, ranolazine, sertindole, simvastatin, terfenadine, or triazolam; colchicine in patients with varying degrees of renal or hepatic impairment.