What is Sertaconazole Nitrate 2% Cream Sertafix®
Sertafix® Cream contains sertaconazole, an antifungal that is used to treat fungal infections of the skin, caused by the dermatophyte fungus Tinea. Side effects were rarely reported with sertaconazole therapy, but may include contact dermatitis, burning on application site and skin dryness.
Sertaconazole Nitrate 2% Cream Sertafix® is used as a topical treatment for fungal infections of the skin, due to the Tinea fungus in immunocompetent individuals. Tinea is a dermatophyte fungus also known as ringworm that causes fungal infection in different parts of the body including ringworm of the foot, also known as Athlete’s foot (tinea pedis), of the body (tinea corporis), of the groin (tinea cruris or jock itch), and of the scalp (tinea capitis). Symptoms of athlete’s foot, named because it is common in people active in sport, include red, inflamed and itchy skin and if the fungus spreads between the toes, it causes the skin to become cracked and peeling which can make the skin raw and painful. Sertaconazole Nitrate 2% Cream Sertafix® relieves symptoms of fungal infection, including pain and inflammation.
Brand names: Ertaczo, Dermofix, Konzert, Zalain, Onabet
How does Sertaconazole 2% Cream work?
Cream Sertafix® contains sertaconazole two percent, a synthetic broad-spectrum antifungal belonging to the imidazole class of antifungals that is used to treat fungal infections of the skin1. Sertaconazole in Sertafix® cream prevents the growth of dermatophyte fungi by inhibiting the synthesis of ergosterol, an important component of the fungal cell membranes that is not found in animal cells. This results in altering the permeability of the fungal cell membrane causing it to become weakened, so that the cell contents leak out, which kills the fungus. It is also thought that sertaconazole in Setafix Cream helps form pores in the fungal cell membrane which also contributes to making the membrane leaky. These actions of sertaconazole in Sertafix® cream prevent the infection from spreading and relieve symptoms caused by the fungal infection, including pain and inflammation.
What are the side effects of Sertaconazole Cream?
The most commonly reported side effects when taking Sertafix Cream include, burning sensation or irritation at the site of application, such as dry skin, redness, burning, pain and swelling.
You should not use Sertaconazole Nitrate 2% Cream Sertafix® if you:
- are allergic to sertaconazole or other imidazole antifungal or any ingredients in Sertaconazole Nitrate 2% Cream Sertafix®
- are pregnant or are breastfeeding, without discussion with your doctor
How to use Sertaconazole Nitrate 2% Cream?
You should apply thin film of your Sertaconazole Nitrate 2% Cream Sertafix® to the affected area and rub gently into the skin once or twice daily depending on what you are being treated for and the severity of the infection. You should continue your course of treatment with Sertafix Cream for up to 4 weeks, depending on what you are being treated for and your doctor’s recommendation, until signs and symptoms of the infection have disappeared, which may be up to 6 weeks. Wash your hands to prevent spreading the infection and do not get the cream into your eyes. You should continue your course of treatment with Sertafix Cream for 2-6 weeks, depending on what you are being treated for and your doctor’s recommendation, until signs and symptoms of the infection have disappeared.