Description
What is 1% Butenafine Hydrochloride Cream Fintop®
Fintop® Cream Butenafine 1% Topical is used for the treatment of fungal infections on the skin, such as ringworm infections, jock itch, pityriasis and other fungal infections as well. Butenafine Topical works by preventing the growth of the fungus. Butenafine Hydrochloride 1% topical cream does this by preventing the synthesis of the fungal cell-protective covering, therefore, making the cells susceptible to harm and killing the cells in this process, this stops the fungal infection from spreading any further. Some of the side effects that may be experienced while using Butenafine Hydrochloride Cream are itching, burning sensation, redness, swelling, blistering.
Butenafine is indicated for the topical treatment of tinea (pityriasis) versicolor due to Malassezia furfur, as well as athlete’s foot (Tinea pedis), ringworm (Tinea corporis) and jock itch (Tinea cruris) due to Epidermophyton floccosum, Trichophyton mentagrophytes, Trichophyton rubrum, and Trichophyton tonsurans. It also displays superior activity against Candida albicans than terbinafine and naftifine. Butenafine demonstrates low minimum inhibitory concentrations against Cryptococcus and Aspergillus. There is some evidence that it is effective against dermatophyte infections of the toenails, but needs to be applied daily for prolonged periods (at least one year).
Like the allylamine antifungals, butenafine works by inhibiting the synthesis of ergosterol by inhibiting squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes. Lacking ergosterol, the cell membranes increase in permeability, allowing their contents to leak out. Furthermore, inhibition of squalene epoxidase leads to a toxic buildup of squalene. This double action of butenafine (increased membrane permeability and toxic buildup of squalene) makes butenafine fungicidal rather than merely fungistatic. In addition to being an antifungal, butenafine is an anti-inflammatory. Because fungal skin infections are often accompanied by significant inflammation, this is a desirable property. The fact that butenafine has intrinsic anti-inflammatory properties is also desirable since it is not necessary to add cortical steroids (which decrease the ability to fight infection) to reduce inflammation.
Brand names: Lotrimin Ultra, Mentax, Butop
How to use Butenafine Hydrochloride 1% Cream Fintop®
Use this medication on the skin only. Clean and thoroughly dry the area to be treated. Apply a thin layer of the medication to and around the affected area and gently rub in, usually 1 to 2 times daily as directed on the product package. If you are uncertain about any of the information, consult your doctor. If your doctor has prescribed this medication to you, then use as directed. Wash your hands after using unless the area to be treated includes the hands. Do not wrap, cover, or bandage the area unless directed to do so by your doctor. Do not apply the medication in the eyes, nose, or mouth, inside the vagina, or on the scalp. If you do get the medication in those areas, flush with plenty of water. The dosage and length of treatment depend on the type of infection being treated.
Fintop® Cream is for external use only. You should use it in the dose and duration as directed by your doctor. The amount you need, and how long you take it will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer of the medicine. You should avoid getting in contact with your mouth, eyes, and nose. In case of accidental contact, wash it off with plenty of water. Keep using it regularly to get the most benefit.
