Decintas® Decitabine Injection

Description

What is Decintas® Decitabine Injection?

Decitabine, sold under the brand name Dacogen among others, acts as a nucleic acid synthesis inhibitor. It is a medication for the treatment of myelodysplastic syndromes, a class of conditions where certain blood cells are dysfunctional, and for acute myeloid leukemia (AML). Chemically, it is a cytidine analog.

Decintas® Decitabine Injection is used in the treatment of blood cancer called acute myeloid leukemia (AML). It is also used to treat patients with myelodysplastic syndrome (MDS). It may be used to treat other conditions, as determined by the doctor.

Decintas® Decitabine Injection is also used with certain other medicines as part of combination chemotherapy. It is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, fever, and lung infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, increasing susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other drugs can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is essential to avoid pregnancy.

Benefits of Dacogen Generic (Decitabine Injection)

In Myelodysplastic syndrome. Decintas® Decitabine Injection is used to treat myelodysplastic syndrome, a group of conditions in which the bone marrow produces blood cells that are abnormal in structure and function and does not produce enough healthy blood cells. Decintas 50 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Blood cancer. Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Decintas 50 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bother you.

Off-label topical use in scar therapy. According to study research treatment enhanced hair follicle regeneration in healed wounds. Decitabine (dissolved in DMSO or sterile vehicle) was applied topically to the wound site, once a day, for 2 consecutive days at the time of scab detachment. Decitabine treatment at all doses tested greatly enhanced hair follicle (HF) neogenesis compared to the vehicle control, with the strongest enhancement seen with the highest tested dose. Decitabine (dissolved in DMSO) was applied topically to the wound site, once a day, for 5 consecutive days at the time of scab detachment. While the two lower doses showed little effect on the regeneration, the highest dose still enhanced hair follicle regeneration.