What is Choltran® Cholestyramine Powder for Oral Suspension?
This medication comes as a powder that you mix with a non-carbonated drink or applesauce and take by mouth. Cholestyramine is used to treat high cholesterol (hyperlipidemia) and itching caused by partial bile obstruction.
Colestyramine (INN) or cholestyramine (USAN) (trade names Questran, Prevalite, Questran Light, Novo-Cholamine, Cholybar, Olestyr, Locholest) is a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption. It is a strong ion exchange resin, which means it can exchange its chloride anions with anionic bile acids in the gastrointestinal tract and bind them strongly in the resin matrix. The functional group of the anion exchange resin is a quaternary ammonium group attached to an inert styrene-divinylbenzene copolymer.
Colestyramine removes bile acids from the body by forming insoluble complexes with bile acids in the intestine, which are then excreted in the feces. As a result of this loss of bile acids, more plasma cholesterol is converted to bile acids in the liver to normalize levels. This conversion of cholesterol into bile acids lowers plasma cholesterol levels.
Choltran Powder for Oral Suspension is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart attack or stroke.
Choltran Powder for Oral Suspension may also be used to treat itching seen in certain types of liver disease and to relieve some types of diarrhea. This medicine may be used alone or in combination with other medicines. It may be taken with a meal or on an empty stomach. You can take it at any time of day but try to take it at the same time each day. Most people with high cholesterol do not feel ill, but if you stop taking this medicine, your condition could get worse. This may lead to your cholesterol levels creeping up again and increase your risk of heart disease and stroke.
It is important to have your cholesterol levels checked regularly. This medicine is only one part of a treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat.
The most common side effect of this medicine is constipation. However, some patients may also experience nausea, vomiting, diarrhea, bloating, or indigestion. Before taking it, let your doctor know if you are suffering from any liver or kidney disease. Pregnant and breastfeeding women should consult the doctor before taking this medicine.
In High cholesterol: Choltran Powder for Oral Suspension effectively reduces the high cholesterol levels in your body. Lowering the amount of cholesterol reduces the chances of heart disease and helps you remain healthier for longer. Take it regularly and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine. Keep taking it even if you feel well.
Choltran Powder for Oral Suspension is a bile acid binding agent. It removes bile acids from the body. The liver then produce more bile acids using cholesterol, as a result, the levels of cholesterol in the body is lowered.
Important warnings Cholestyramine Powder
Complete biliary obstruction: You shouldn’t take this drug if you have a full blockage of your bile ducts that don’t allow bile to be released into your intestine.
Low vitamin levels: This drug may stop your body from absorbing vitamin K and folate (a form of vitamin B). Low levels of these vitamins can be harmful and make you more likely to bleed or bruise if you get hurt. Your doctor will let you know if you need to take extra vitamins.
High acid levels: This drug can increase the acid levels in your body. Tell your doctor if you have low energy, headaches, nausea, or vomiting when you take this medication.