What is Cilamin® Penicillamine 250mg (Cuprimine Generic)?
Cilamin® Penicillamine 250mg Oral Capsule works by blocking the action of certain chemical messengers that are responsible for inflammation and slows the progress of the condition with certain joint diseases. It works in Wilson’s disease by helping the body to remove excess copper.
Cilamin® Oral Capsule (Penicillamine 250mg) is a type of medicine called a copper-chelating (pronounced “key-lating”) agent. This means the medication binds to copper in body tissues where it has built up and carries it into the bloodstream, which carries the bound copper to the kidneys, which filter it into the urine.
Benefits of Penicillamine 250mg Cuprimine Generic
In Rheumatoid arthritis. Cilamin® Oral Capsule reduces pain, stiffness, and swelling in your joints and slows down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improves your symptoms.
In Wilson’s disease. Wilson’s disease is a disease in which excess copper builds up in the body. Cilamin® Oral Capsule helps to remove this excess copper from the body and helps relieve symptoms such as swelling, fatigue, abdominal pain, and uncontrolled or poorly coordinated movements. It also helps reduce pain, stiffness, and swelling in your spine and joints. Additionally, it improves flexibility and prevents disease progression. This will help you lead a better and active life.
What is Wilson’s disease?
Wilson’s disease is a genetic disorder in which there is decreased excretion (elimination of waste matter) of copper into bile; this results in the buildup of copper to toxic levels in the liver, brain, and/or other organs.
Copper enters our bodies through the food we eat; this is normal and necessary because the body needs copper to ensure our cells work properly and to make proteins, nerve cells, and the pigments that color our skin, eyes, and hair.
Copper plays a particularly important role in the development and maintenance of the central nervous system. However, the average diet contains more copper than the body needs. In most people, the liver processes the necessary amount and excretes the leftover copper into the bile, which passes out of the body in feces.
- About 1 out of every 30,000 people worldwide has a genetic mutation that causes a breakdown in the body’s normal mechanism for removing the excess copper.
- More than 500 different mutations can cause Wilson’s disease, but all of them affect a gene called ATP7B, which can be found on chromosome 13 in human cells.
- The gene tells the body how to make a protein of the same name that is responsible for removing copper from the body.
- The mutations that cause Wilson’s disease are autosomal recessive, which means that a person with Wilson’s disease will have inherited 2 copies of Wilson’s disease mutation, 1 from each parent.
- Parents and siblings of individuals with Wilson’s disease may or may not have the disease, depending on whether they also carry 2 copies of the mutation.
- Someone with only 1 copy of Wilson’s disease mutation will metabolize copper normally, but there is a risk of passing the condition onto one’s children.
- Wilson’s disease is fatal if not treated, so getting a correct diagnosis is essential. Once it’s diagnosed, Wilson’s disease can be effectively treated with a low copper diet and medicines called chelating (pronounced “key-lating”) agents that bind to copper and carry it out of the body.
Indication of Cuprimine Generic
Cilamin® Oral Capsules (Penicillamine 250mg) are used to treat Wilson’s disease (a disease where there is too much copper in the body), cystinuria (a disease where an excess amount of certain proteins are in the urine), and patients with severe, active rheumatoid arthritis who have not had a response to other therapy. Not enough evidence is available to see an effect on the treatment of ankylosing spondylitis.
Warning. Important safety information: You should be under the close supervision of your doctor when you are taking Cilamin® Oral Capsules (Penicillamine 250mg). Report any side effects promptly to your doctor.
- Do not take Cilamin® Oral Capsules (Penicillamine 250mg) if you are pregnant unless you are taking Cilamin® Oral Capsules (Penicillamine 250mg) to treat Wilson’s disease (too much copper in the body) or cystinuria (too much protein in the urine). Mothers on therapy with penicillamine should not nurse their infants.
- Cilamin® Oral Capsules (Penicillamine 250mg) can cause serious blood disorders, and some can be fatal. If you have had aplastic anemia (anemia due to lack of all blood cells) or agranulocytosis (lack of certain white blood cells) and it was related to taking Cilamin® Oral Capsules (Penicillamine 250mg) , you should not take it again.
- Cilamin® Oral Capsules (Penicillamine 250mg) can cause kidney damage and should not be used to treat rheumatoid arthritis if you have a history of kidney disease. If you take Cilamin® Oral Capsules (Penicillamine 250mg) to treat cystinuria, routine analysis of your urine may be necessary and you should have an x-ray every year to check for kidney stones.
- Cilamin® Oral Capsules (Penicillamine 250mg) can be associated with fatalities due to other diseases such as Goodpasture’s syndrome (an immune disease that attacks the lungs and kidneys) and myasthenia gravis (an immune disease affecting the muscles). Your doctor may order blood analysis on a regular basis.
- Cilamin® Oral Capsules (Penicillamine 250mg) can affect how your liver works. Tests to determine how your liver is working should be done regularly.
Tell your doctor right away if you experience: blood in your urine, unexplained cough or wheezing, coughing up blood, shortness of breath, muscle weakness, drooping eyelids, double vision, watery blisters on the skin or other rash, fever, joint pain, swollen lymph nodes, mouth ulcers, or diminished taste.
Cilamin® Oral Capsules (Penicillamine 250mg) is a drug that has many side effects, and some can be fatal. Other side effects that can occur include serious lung problems, nervous system symptoms, diseases of the skin and mucous membranes known as pemphigus, allergic reactions (including a condition known as drug fever as well as skin rashes), mouth ulcers, and loss of taste. Talk to your doctor if you experience side effects and also about possible side effects that could occur. Ask your doctor or pharmacist for product labeling written for professionals for a full list of potential adverse reactions.
Tell your doctor about all other medicines (prescription and over-the-counter, including vitamins and herbal supplements) that you are taking. Some medicines (such as gold therapy, antimalarial or cancer drugs, oxyphenbutazone, or phenylbutazone) should not be used with Cilamin® Oral Capsules (Penicillamine 250mg) because they also may cause serious liver and kidney side effects.