Tretin® Tretinoin Emollient Cream

Topical Tretinoin USP 0.025% / 0.05%

4.23 out of 5

(62 customer reviews)

From USD $30.00 (EUR €28.50)

✓ Mild and moderate strengths available in a creamy base

✓ Chemical skin exfoliator peel cream

✓ Retinoic acid cream suitable for acne/wrinkle treatment

✓ Extremely effective in combating signs of aging

✓ Acne and after-acne treatment solution

✓ Works by increasing the skin cell turnover rate and helps gently exfoliate the skin

Tretin cream in a big 30g tube with tretinoin (aka Yellow peel or Retinol peel) concentration equal to 0.025% or 0.05% is made by reputable H&H Company. Tretinoin widely used as a chemical peel component for skin peeling procedures. The main ingredient is retinoic acid (Vitamin A or stable strong medical grade Retinol).

Retinoic acid peels effectively cleanse the skin, regenerate skin cells, has anti-inflammatory effects, makes skin glow, improves skin texture and structure, provides a lifting effect. Use tretinoin cream only when prescribed by your dermatologist.

Size: 30g / 1.05oz
Brand name: Retin-A Cream, Avita, Refissa, Atralin, Tretin-X, Rejuva-A, Stieva-A
Title Range Discount
Items: 2 - 4 5%
Items: 5 - 8 10%
Items: 9 + 15%


What is Tretin® tretinoin 0.025-0.05 retinol cream?

Tretin tretinoin cream is used to treat fine wrinkles, dark spots, or rough skin on the face caused by damaging rays of the sun. It works by lightening the skin, replacing older skin with newer skin, and by slowing down the way the body removes skin cells that may have been harmed by the sun. Tretinoin cream works best when used within a skin care program that includes protecting the treated skin from the sun. Tretin is available without prescription in okdermo skincare store.

Tretinoin is generally used to treat acne, keeping skin pores clear. When used correctly, Tretin cream does amazing things for the skin.  Tretinoin has proven itself to reduce, reverse, and prevent wrinkles, it’s never too late to start using it. Brand names – Atralin, Avita, Refissa, Renova, Retin-A, Tretin-X, Rejuva-A, Stieva-A cream, Vitamin A Acid.

All-trans-retinoic acid, aka tretinoin, is an active form of retinol (vitamin A). In nature, it can be found both in vegetable substances and in animal products. It is capable of making bonds with nuclear receptors and initiating a cellular response with their help. It is worth mentioning that almost all cells in a body are sensitive to tretinoin. To prevent it accumulation in tissues, which in many cases may lead to various side effects, only a small amount of products should be used in particular areas only. The result of Tretin cream application is active exfoliation, which leads to epidermis renewal at the cellular level, the quality of the extracellular matrix of the dermis is also considerably improved.

Retinoic acid is a chemical peel and belongs to skin treatments with a short recovery period. Retinoids (synthesized equivalents of vitamin A) regulate the processes of differentiation, proliferation, and intercellular communication. When retinoids get into a cell, they make a bond with nuclear sensors. As a result, particular sections of the cell genome are activated or decelerated.

Since the main effect of retinoids on cells is produced through nuclear sensors (through nuclear receptors and specific molecular activation mechanisms), they can be included in the same category as thyroid and steroids. The main advantages of this treatment are minimal skin damage, a brief recovery period, and a low probability of complications.

  • Tretin cream (Retin-A) is clearly a powerful skin care treatment, but there are tricks for using it to get the greatest benefits.
  • Always apply it to your skin at bedtime. Never use it during the day and totally avoid the sunlight.
  • Never layer tretinoin with benzoyl peroxide and ideally don’t apply it when you also have acid products on your skin like vitamin C, glycolic acid or salicylic acid.
  • Always wait at least 15-30 minutes after cleansing and applying any other skincare products to your skin before you apply tretinoin cream.

Tretin® is a topical tretinoin emollient cream used to treat acne, oily skin blackheads. Tretinoin is a vitamin A derivative that has recently become a popular ingredient in age-fighting skincare products. Topical use of vitamin A derivatives reduces fine lines and wrinkles appearances. Additionally, it brightens the skin, which leads to the subsequent clearance of discolorations and dark spots.

Tretinoin in Tretin® topical cream is available in two strengths. Higher concentrations are associated with increased efficiency but also more irritation and side effects. Tretinoin’s primary use is acne. It acts on the skin to quickly and efficiently remove acne pimples. It also clears skin pores, tightening the skin and making it more difficult for more acne pimples to develop.

In addition to its acne therapeutic effect, tretinoin fights skin aging. It reduces inflammation and boosts collagen and elastin production in connective tissue. Tretinoin induces biological reactions that result in toned facial skin and firmer complexion.

Tretinoin is a topical cream/gel used to treat acne, sun damage, and fine lines. It belongs to the retinoid family, which are Vitamin A derivatives. Vitamin A is essential in many biological processes, particularly in cells covering epithelial surfaces like the skin. It regulates collagen production in connective tissue and the rate of skin cells turnover in the deep dermal layers.

Tretinoin is sold under many brand names, including Retin A, Renova, and Tretiheal. It is also available in three potencies 0.025%, 0.05%, 0.01%. Tretinoin works by irritating the skin. Thus, higher concentrations cause more irritation and subsequently have high efficiency.

The sustained application of tretinoin for more than six months manifests in thicker, firmer, and brighter skin, more glowing, and lesser fine lines as well. Tretinoin not only prevents photoaging but also corrects the damage caused by sun exposure. It cleans the splotches, discolorations, and dark spots, leading to a luminous and brighter tone.

By increasing dermal thickness, wrinkles and fine lines are less likely to develop. Tretinoin boosts the cell s abilities to produce collagen, which is the milestone of complexion elasticity and firmness. It is the building block of connective tissue. Increasing collagen production is the mechanism behind enhanced skin thickness. With increased collagen content, the skin becomes more toned and elastic. It regains its youthful and glowing appearance.

In addition to fighting aging signs, tretinoin is a popular acne treatment. It clears whiteheads and blackheads that may lead to acne eruptions, reduces sebum production. It makes skin pores expel their contents. With tighter pores and no oil secretion, acne pimples are less likely to erupt. Tretinoin modifies the complexion texture to bring a new, long-lasting, naturally bright skin appearance.

Tretin® Tretinoin Emollient Cream

Okdermo is your source for the leading skincare products. We partner with the best companies to ensure we consistently carry and deliver the highest quality products to our customers. Tretin® Tretinoin Emollient Cream is an effective treatment for improving texture, reducing inflammation in the skin, and leaving the skin with a healthy, smooth glow. Tretin® Tretinoin Emollient Cream is made by a reputable company and has been proven to help improve the overall texture and appearance of the skin.

If you are looking for a good peel that will change the way your skin looks, check with your dermatologist to see if Tretin® Tretinoin Emollient Cream is right for you.

Features of Tretin® Tretinoin Emollient Cream

  • The creamy base comes in mild and moderate strengths
  • Chemical peel cream that exfoliates the skin on a deeper level
  • Retinoic acid cream that helps reduce acne, fines lines and wrinkles
  • Increases cell turnover and exfoliates the skin to reveal fresh new skin
  • Tretin® Tretinoin Emollient Cream is available for purchase without a prescription here at Okdermo.

Tretin® Tretinoin Emollient Cream Uses

Tretin® Tretinoin Emollient Cream is used to get rid of the top layer of skin, revealing new, youthful skin below. It can be used for the following:

  • Acne treatment, keeping the skin pores clear and tightening the skin to reduce future breakouts
  • Reduce fine lines, wrinkles, and other signs of aging
  • Treat dark spots caused by sun damage
  • Brighten the skin
  • Increased cell turnover to reveal new youthful, glowing skin
  • Reduce inflammation, swelling, and redness
  • Boost collagen to enhance tone, elasticity, and firmness in the skin

How to Use Tretinoin Cream

If you are planning to use Tretin® Tretinoin Emollient Cream as part of your skin regime, it is important that you keep out of the sun and use good sunscreen to protect the skin. it is a powerful skin treatment, so there are a few things you want to make sure you do:

  1. Use a good sunscreen and avoid direct sunlight
  2. Apply before bed, never apply in the daytime
  3. Do not use in conjunction with benzoyl peroxide or other strong products like Vitamin C, glycolic acid or salicylic acid
  4. Wait at least 15-30 minutes after washing your face or applying other skincare products to your face before applying Tretinoin to the skin
  5. You can get the cream in two different strengths. Keep in mind, that the stronger it is, the more irritation and potential side effects there are.

What to Expect When Using Tretinoin Cream

If you are starting a Tretinoin regime, it is important to know that if not used correctly, issues can occur. Tretinoin is a powerful cream and can cause severe irritation. When you first start using Tretinoin, use small, pearl-sized portions for the face, neck, and chest. You will likely experience irritation and scaliness. If it gets severe, scale back on the amount and frequency of use. It is important to pay attention to your skin and adjust as you need. Once your skin fully adjusts, the goal is to get to a place where you can apply it every night before bed.
Always consult your dermatologist before starting Tretinoin on your own.

Tretinoin Skin benefits

Tretinoin s anti-acne and anti-sun damage effects result from a shared mechanism, which is enhanced cellular turnover. As the largest organ in the body with a wide surface exposed to the outside world, the skin requires constant maintenance.

Newly-made cells continually travel to the surface to replace worn-out and dead cells. Tretinoin boosts up this process. That is the reason is why many people experience peeling and exfoliation. It is a side effect of the skin adapting to a new rate of the cell cycle.

The rapid cellular turnover translates to an additional thickness to the dermal and epidermal layers in contrast to the outermost layer (stratum corneum). With a substantial supply of new and fresh cells, the superficial layers peel off and are less likely to build up within skin pores and blackheads.

Tretinoin prevents acne by fending off its triggers. As the detachment of dead cells becomes facilitated, they are less likely to build up and clog the pores and follicles. The sebum conduits expel their contents, and bacteria find the environment arduous for proliferation.

Tretinoin fends off aging signs, particularly the ones caused by sun exposure. UV light promotes collagen breakdown and blocks the skin repairing abilities. Tretinoin counteracts sun damage by restoring the supply of collagen and reducing inflammation, which helps skin cells regeneration and renewal.

What is Tretinoin?

Tretinoin belongs to the vitamin A derivatives family called retinoids. It is a first-generation retinoid.

Vitamin A is essential for many biological reactions, particularly for the growth and maturation of epithelial cells. Tretinoin acts on the way skin cells regenerate and replace old surface cells. It affects the deep progenitor cells, leading to a rapid cell cycle.

The FDA has approved tretinoin as a safe and efficient treatment for most skin conditions associated with oily skin, such as acne, black or whiteheads.

How Does Tretinoin Work?

Tretinoin works by changing the way skin cells develop and mature as well as reducing oil levels. Scientists are unsure of how tretinoin use results in many skin modifications. By increasing skin cells turnover, many downstream effects follow, such as:

  • Tretinoin increases the shedding of surface, dead cells: by enhancing the production of new cells, tretinoin facilitates the replacement of old cells, no longer functional due to constant tear and wear by a new supply of healthy cells.
  • Tretinoin reduces inflammation: swelling, redness, and inflammatory mediators are all side effects of immune system response that may damage skin cells. Tretinoin relieves unnecessary inflammation, which allows the optimal function of skin cells.
  • Tretinoin boosts collagen and elastin production: the building block of most of the body s connective tissues is collagen. It is a component of ligaments, bones, and soft tissues. Collagen is the agent that confers to the skin its youthful consistency. Higher collagen levels mean enhanced tone, elasticity, and firmness.

Tretinoin fights aging signs

With a large surface to protect from UV light and the external environment, the skin is a large organ in a constant state of regeneration and repair. Similar to all biological processes, the skin s self-renewal abilities decline with age.

One study included two randomized groups, One received non-specific skincare treatment, and the other applied tretinoin 0.02% for eight months. Both groups showed visible skin improvements, but the tretinoin group saw a significant reduction in periorbital wrinkles after the treatment.

In conclusion, Tretin tretinoin topical cream is a skincare product with a versatile use: a potent antiacne treatment and safe aging signs fighter.

Benefits of using tretinoin 0.025-0.05 retinoic acid peel

  • Tretinoin helps to lighten the skin and prevent age spots by the way of exfoliating and deep chemical penetration capabilities.
  • Tretinoin builds collagen to thicken and increase the structural strength of treated skin.
  • Tretinoin helps to decrease a person’s risk of developing skin cancer. (This should be reason enough!)
  • Skin just looks better and younger when using tretinoin.

Despite the many benefits of Tretin cream therapy to prevent wrinkles and other issues of aging skin, it can result in some issues if it’s not used correctly. For instance, when starting tretinoin therapy, you need to begin with “pearl-sized” portions for the face, neck, and chest. It is important to begin using it gradually to allow your skin to adjust. Its recommended to use it twice a week (every third night) for the first couple of months. During this time, understand that a little scaliness and irritation is normal at first, but if the treated skin becomes really sensitive, back off the Tretinoin for a bit. Let your skin return to normal before you begin the treatment again. As your skin adjusts, slowly try to increase to using it every night.

Always consult to your dermatologist prior start using any tretinoin products topically.

When to use Tretin® tretinoin 0.025-0.05 retinoic acid peel

  • Lack of collagen production;
  • Disruption of the skin’s natural moisture balance;
  • Mimic wrinkles;
  • Loss of skin elasticity and strength;
  • Need for skin whitening;
  • Excessive pigmentation caused by solar radiation;
  • Skin aging and photoaging;
  • Acne and problematic skin;
  • Acne scars treatment;
  • Hyperpigmentation;
  • Hyperkeratosis.

Contraindications for Tretin® tretinoin 0.025-0.05 retinol cream

  • Various allergies – indicate the probability of severe skin reaction to the treatment, also increased with the use of retinoids that makes skin more reactive;
  • Atopic skin, eczema, seborrheic dermatitis, etc. – indicate skin hypersensitivity (reactivity);
  • Viral infections – under the influence of retinoids and acids, can cause herpes lesions in patients with a history of herpes;
  • Warts – can cause further viral shedding from a wart;
  • Photosensitivity – high skin sensitivity to solar or other types of UV radiation;
  • Compatibility with pharmaceutical products – those who have taken Roaccutane should wait at least half a year before getting a retinoic acid peel;
  • Liver diseases, including previous hepatitis infections;
  • Pregnancy or pregnancy planning within a year, as well as lactation, for retinoids, are embryotoxic, do not use Tretin cream if you are pregnant or planning to become.

Related resources/references:

  1. Retin-A cream User Guide
  2. Retin-A vs Retin-A Micro®
  3. Tretinoin cream for wrinkles
  4. Retin-A tretinoin: Cream vs Gel
  5. The difference between Retin-A and Tretinoin
  6. How to minimize irritation/redness with Retin-A
  7. Everything you need to know about Retinol & Retinoids
  8. User reviews for Retin-A
  9. Retin-A (Topical)
  10. Retin-A (Gel)
  11. Tretinoin (Topical)
  12. Acne treatment with tretinoin
  13. Retin-A side effects

Additional Information


  • Tretinoin USP 0.025 or 0.05  w/w
  • Preservative Sorbic acid IP 0.20% w/w
  • Preservative Butylated Hydroxytoluene IP 0.10% w/w
  • Cream base q.s.
  • Adequate average added

Apply as directed by your dermatologist.