Procdina TX® Tablets 1×30

Tranexamic Acid 250mg

5.00 out of 5

(3 customer reviews)

USD $33.00 (EUR €28.05)


Low-dose oral tranexamic acid can serve as a safe and useful adjunct in the treatment of refractory melasma according to the science article and experiment by National Skin Centre, Singapore.

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Items: 2 - 4 5%
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Items: 9 + 15%


What is Tranexamic Acid 250mg Tablets Procdina TX®

Tranexamic acid is used to treat heavy menstrual bleeding in women. This medicine may be used by teenage females, but is not intended for use before the start of menstruation. Tranexamic acid is an antifibrinolytic agent. It works by blocking the breakdown of blood clots, which prevents bleeding.

Brand names: Lysteda

Oral tranexamic acid lightens refractory melasma

Melasma is a common acquired hyperpigmentary disorder, particularly among Asians and Hispanics, but its exact pathomechanism is poorly understood. Tranexamic acid has been found to lighten melasma by interfering with the interaction of melanocytes and keratinocytes by inhibiting the plasminogen/plasmin system. The aim was to evaluate the therapeutic effects of oral tranexamic acid in the treatment of melasma refractory to topical skin-lightening agents.

The retrospective study analyses patients with melasma recruited from a tertiary dermatological center in Singapore between 1 August 2009 and 31 March 2011. The patients chosen had refractory melasma treated with oral tranexamic acid 250 mg twice daily in addition to pre-existing combination topical therapy. Objective assessment using the physician’s global assessment and melasma area and severity index (MASI) scores were performed based on a post-hoc analysis of photographic records by three independent physicians. A paired t-test was used to evaluate the changes in the MASI scores pre-therapy and post-treatment. Statistical significance was defined as P < 0.05.

Altogether 25 patients were treated with tranexamic acid for a mean period of 3.7 ± 0.33 months, in addition to combination topical therapy. Their mean age was 47.2 ± 1.61 years. The mean MASI scores after tranexamic acid treatment (2.7 ± 1.6) were significantly lower (P < 0.01) than those prior to treatment (8.8 ± 4.2). The mean improvement in scores was 69%. The follow-up period was up to 6 months. Low-dose oral tranexamic acid can serve as a safe and useful adjunct in the treatment of refractory melasma.


Tranexamic Acid 250mg

3 reviews for Procdina TX® Tablets 1×30

  1. 5 out of 5

    Brian Johnson

    I have had a fair number of basal cell skin cancer spots removed. These are from X-Ray therapy for acne back in the ’70s. A dermatologist who does a lot of research studies said that Grape Seed Extract is great for that specific situation. I have been taking them for years now and the incidence of skin cancer has dropped to almost zero. What a relief. Now I cannot say that this tablet is better than any other. Who knows? But grape seed extract is a regular supplement for me going forward.

  2. 5 out of 5


    It is a very good anti-oxidant with good science behind it. But it can be expensive and hard to find. This has been a reasonably priced reliable source, thanx okdermo!!

  3. 5 out of 5


    Very good! Easy to take and was delivered fast.

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