Supatret® Tretinoin Micro Gel

Tretinoin Microspheres 0.04% / 0.1% USP

4.60 out of 5

(53 customer reviews)

From USD $33.00 (EUR €31.35)

Brands:Sun Pharma

✓ Two strengths | Non-oily water base

✓ Advanced chemical exfoliator peel gel w/o preservatives

✓ Microsponge® technology – action without irritation

✓ Deeper skin penetration, faster action w/o dryness & redness

✓ Strong acne, wrinkles, and hyperpigmentation fighter

✓ Proven to help you get the powerful results you want

✓ Reputable manufacturer Sun

Retin-A Micro contains different concentrations of 0.04% – 0.1% tretinoin belongs to a family of retinoids, also known as Retinol, Vitamin A cream, Retinoic Acid or Yellow peel is a long-time skincare staple, and as most dermatologists suggest, should be included in a person’s everyday routine.

A strong cosmeceutical skincare solution for your skin Retin-A Micro 0.04% or 0.1% tretinoin Supatret Microsphere gel  – the most technologically advanced time-release formula with the micro-gel base to penetrate deeper into the skin and absorb faster with special Microsponge delivery system.

Size: 20g / 0.7oz
Brand name: Retin-A Micro Gel, Atralin, Renova, Avita
Title Range Discount
Items: 2 - 4 5%
Items: 5 - 8 10%
Items: 9 + 15%



Retin-A Micro Supatret gel originally prescribed to help fight acne, this topical gel is also an effective wrinkle fighter and helps improve overall skin tone, also tretinoin is very effective against melasma and different types of skin hyperpigmentations due to its skin exfoliating and penetrating capabilities.

Retin-A Micro® is a vitamin A derivative and part of the retinoid family, Supatret .04 – .1 percent tretinoin micro gel works by increasing skin cell turnover, and a dermatologist may help determine which one is right for you. Retin-A Micro tretinoin 0.04/0.01 gel is often applied at night in very small amounts. It’s typically recommended to use only a pea-sized amount and spread a super light layer on your face. Because retinoids increase sun sensitivity, it is crucial to wear ample sunscreen every day, even in winter or when it’s overcast. Most dermatologists recommend at least SPF 30 sunscreen when used with retinoids.

Microsphere Gel (Micro® formulation) contains micronized yellowish color tretinoin molecules which can penetrate deeper into the epidermis and deeper skin layers, it is a time-release form. Tretinoin is one of an acids family called retinoids, powerful exfoliant, and is effective in preventing acne and healing different skin imperfections.

While you are adjusting to Supatret Retin-A micro gel you might experience some skin redness, dryness, itching, scaling, or even find that skin conditions worsen during your first few weeks of wrinkle treatment. Stick with it. Results often take several weeks to appear. You may start by applying the product every other night, or ask your dermatologist about using a lower dose or weaker strength, to help the adjustment period.

All-trans-retinoic acid aka tretinoin component is important in terms of not only increasing skin-cell growth rate but increasing cell membrane nutrients to increase oxygen transport, which supports the collagen matrix. It is a daily aid to keep the cells functioning properly, not just increasing cell turnover. The skin-cell maturation process may take 21 days. But the movement of cells and maturation is hourly, daily, weekly, and monthly. Different cells are transforming all the time, every second. When the primitive look is to say cell turnover is every 28 days — it’s every second. The pure retinol (retinoic acid or tretinoin) is the skin product that allows that and it should be included in everyone’s anti-aging skin care regimen if the dermatologist prescribed it to you. Always consult your dermatologist first prior start using any retinoids and tretinoin-containing creams/gels.


Supatret gel aka Yellow peel came in two strengths – moderate 0.04% and strongest available 0.1%, it is a cosmeceutical grade skin care solution for your skin. Microspheres gel has all the capabilities of plain  All-trans-retinoic acid gel but has a new skin penetration and delivery system called Microsponge.

The most technologically advanced time-release formula with a micro-gel base for deeper skin penetration absorbs faster with special Microsponge molecular delivery system. There are three main types of topical tretinoin – a cream, a gel, and a gel Microsphere gel. There is often some confusion when talking about the two gel formats, Tretinoin Gel, and Tretinoin Gel Microsphere. So let’s review the difference between them.

Not all Tretinoin gels are the Microsphere formula. The regular gel is not a time-release formula, and the gel itself contains a high amount of denatured alcohol. Plain old tretinoin gel is clear – you can find it here. The tretinoin gel Microsphere formula does not contain as much denatured alcohol and is an opaque, yellowish color without preservatives. The difference is that tretinoin gel Microsphere aka Micro uses a special delivery system called Microsponge, which is composed of tiny, sphere-shaped particles with a porous surface. The porous surface allows for a sustained flow of the acid out of the sphere and is what makes Microsphere a time-release product. It’s worth noting that the spheres are so small that you cannot see or feel them in the product.


Tretinoin (all-trans retinoic acid) was developed by Dr.Albert Kligman and Dr.James Fulton in 1969 as an acne treatment ingredient and was known under the brand name Retin-A, a brand name that is still the most recognizable of the retinoid products available today. It works as a cell-communicating agent, signaling cells in the deeper layers of the skin to create new, healthy skin cells and increase cellular turnover. It was later discovered that the very mechanism that allows tretinoin eliminate acne also helps heal photodamage, reduce wrinkles, and slow the aging process.

Generally, tretinoin gels used and created to treat acne, but also flawlessly used to reduce and gradually remove the appearance of wrinkles, fine lines, age and sun spots, uneven skin tone, the roughness of facial skin while also facilitating the disappearance of darker and lighter spots on photodamaged skin and hyperpigmented skin. Showing good results in combination with other topical treatments to treat alopecia and other kinds of hair loss. Any tretinoin gel must be used with a total skin care and sunlight avoidance program.

Tretinoin is a very powerful anti-aging treatment agent, as it is the actual pure all-trans retinoic acid, which is derived from Vitamin A. Over the counter retinoids such as retinol are indirect forms of all-trans retinoic acid, meaning that the ingredient itself is not an all-trans-retinoic acid, but your body eventually converts it to one once it’s been absorbed.

A yellow peel is a combination of phytic acid, kojic acid, and azelaic acid or sometimes used just a plain concentrated retinoic acid to achieve the same exfoliating/regenerating results. It is touted as being helpful for melasma. Very few things are helpful for melasma.  Also, certain individuals with darker skin may deperpigment with any peel including this one.


  • Eliminate facial wrinkles – reduced signs of skin aging, collagen production boost, restoration of skin;
  • Reduction and preventing fine lines and wrinkles, improved skin natural elasticity, texture whitish tone, younger looking, glossy, firm, toned and tightened skin;
  • Increase in radiance and luminosity of the facial skin, elimination of dry, rough, scaly skin when used with moisturizers and vitamin serums as a skin care routine;
  • A gradual effective decrease in skin hyperpigmentation such as sunspots, photo-damage, age discoloration spots, and other related dark spots;
  • Acne scars removal, regeneration of damaged skin, enlarged pores tightening;
  • Stretch marks reduction in combination with Vitamin C serums and medical moisturizers;
  • Effective solution against melasma/chloasma and freckles, oily skin conditions;
  • Fast and extremely effective results when used in combination with hydroquinone creams;
  • Good for sensitive, tired and mature skin, in bumpy, rough, uneven skin tone conditions.


  • Treatment for acne prone skin, acne scars, Fordyce spots, deeper lumps (cysts and cystic acne);
  • Blackheads & whiteheads self-removal features, any type of pimples / comedone treatment, pores unblocking;
  • A solution for seborea & seborrheic dermatitis, pearly penile papules, acne conglobata;
  • Pyoderma faciale, any kind of problematic skin, Staphylococcus aureus (golden staph);
  • Demodex treatment – genus of tiny parasitic mites that live in or near hair follicles, face smell;
  • Carbuncles, impetigo, sore, sebaceous, pilonidal sinus, keloid scars, shingles, nodules;
  • Milia, old stretch marks, skin scars, different skin imperfections, skin spots, and marks;
  • Keratosis pilaris, keloid scars, actinic keratosis, seborrheic keratosis, skin large pores tightening.


Tretinoin gel is an active Vitamin A metabolite that affects the way skin cells behave and adapt. Tretinoin in Microsphere gel uses a special delivery system called Microsponge, which is composed of tiny, sphere-shaped particles with a porous surface. The porous surface allows for a sustained flow of the Tretinoin out of the sphere and is what makes tretinoin gel Microsphere a time-release product.

It reduces all symptoms of acne, fine wrinkles and age spots caused by aging or sun damage. Tretinoin prevents different skin disorders by blocking the hardening processes of the outer layer of the skin. It also facilitates the shedding of old skin cells to better promote the formation and growth of new ones (exfoliates the skin). Once we combine all these effects together, we get a product that not only speeds up skin cell turnover, but it also clears up pores from blackheads and whiteheads, pimples and other acne symptoms that could be so hard to get rid of under normal circumstances.

You can buy retin a micro online in skin care store okdermo. Brand names: Retin-A Micro, Renova, Avita, Refissa, Atralin, Obagi.


  • Always consult your dermatologist prior start using any tretinoin-containing solution;
  • Wash the area with warm soapy water or a soap-free cleanser and rinse with water;
  • Remove all cosmetics before applying the gel. Gently dry the area. Wait 15 minutes to make sure that the skin surface is completely dry;
  • Squeeze a small amount (quarter inch or less) of the gel onto your fingertip. This should be enough to cover the affected area;
  • Apply gel or cream to the affected area once a day, preferably in the evening or just before bedtime.


  • Either pregnant or may become pregnant during use, lactation period;
  • Allergic to any of its ingredients or suffering from eczema (tretinoin may cause severe irritation);
  • Suffering from rosacea or perioral dermatitis skin conditions or using any skin peeling cream or other substance that contains resorcinol, salicylic acid or sulfur are, or have been, exposed to sunlight for a longer period of time;
  • Do not use more than once a day. Using more frequently does not improve results and may lead to adverse reactions.

Related resources/references:

  1. Retin-A cream User Guide
  2. Retin-A vs Retin-A Micro®
  3. Tretinoin cream for wrinkles
  4. Retin-A tretinoin: Cream vs Gel
  5. The difference between Retin-A and Tretinoin
  6. How to minimize irritation/redness with Retin-A
  7. Everything you need to know about Retinol & Retinoids
  8. User reviews for Retin-A
  9. Retin-A (Topical)
  10. Retin-A (Gel)
  11. Tretinoin (Topical)
  12. Acne treatment with tretinoin
  13. Retin-A side effects

Additional Information


  • Tretinoin USP  0.04% – 0.1% w/w (as microspheres)
  • Gel base q.s.
  • Without preservatives

53 reviews for Supatret® Tretinoin Micro Gel

  1. 4 out of 5

    Margarita Mullins

    It’s now 3 months since I started using Retin-A. My skin has calmed down with the crazy peeling, and I peel just minimally now. I’ve increased the strength of Retin-A on my forehead to 0.1% because that’s where most of my fine lines were. Overall, my complexion looks smoother, brighter and my wrinkles are much less pronounced. I got carded at the liquor store about a month ago — proof that I’m looking more youthful!

  2. 5 out of 5

    Ira Hale

    I did my research on Retin-A Micro Gel before starting it. I was apprehensive about trying Retin-A, however my acne was so aggressive after quitting birth control I was willing to try anything.

  3. 5 out of 5

    Marsellie France

    Just started using my product, dermatologue recommeneded it, price is great, but so far so good.

  4. 5 out of 5

    Erlinda Sorrell

    After 10 months of Retin-A, my skin is much brighter and tighter. I had a couple of freckles that disappeared, too! My skin tone is nice and even. I get “empty pimples” once a month. But they’re only visible if I can’t resist….. And squeeze. :-p MOISTURE IS EVERYTHING! GET A GOOD HEAVY NIGHT CREAM!

  5. 4 out of 5

    Loan Ashton

    The best skin treatment over

  6. 5 out of 5

    Alana Hutcherson

    It’s taken me awhile to find the perfect routine for my face.. Because I’m now extremely sensitive & dry. But, I finally got it!

  7. 5 out of 5

    Cristal Doll

    I’m 29 and have used Retin-A micro gel 0.04% for 3 years now. I’ve tried everything from Proactive, Accutane and over the counter medicines. Nothing helped me like Retin-A Micro gel. Sure there was an initial breakout in the beginning but now my skin is so smooth, acne free, healthy and bright that I don’t even care about the initial breakout. After 3 months of use I am Acne free thanks to this medication. I will not stop using it.

  8. 5 out of 5

    Annabell Maness

    I’m 23 and have battled all sorts of acne through my life. That came along with some serious scarring. While there is definitely a ways to go for the scarring, its helped tremendously.

  9. 4 out of 5

    Carolyne Seal

    This medication is extremely effective when used properly.

  10. 5 out of 5

    Ivy Hyland

    I was on accutane (isotretinoin) from December 2015 to July 2016. I had severe acne all over my face, chest, back, and shoulders. Post-accutane my skin was clear as water and I got so many compliments on my skin. My skin was clear and I never got one pimple until mid April 2017 I noticed pimples reappearing on my skin. I got in touch with my derm and she prescribed me tretinoin 0.025% and a face wash- sodium sulfacetamide with salycic acid. I am now on 0.04% and I have been on the gel for a little over 8 weeks. I have seen significant improvement since I started and I did experience about a month and a half of initial breakout. I highly recommend this gel and don’t give up! It takes time and my skin is still clearing up. Patience!!!!!

  11. 4 out of 5

    Yuko Hurd

    Retin-A is a life-changer!

  12. 5 out of 5

    Sherlene Kerns

    Got on retinol because of acne scars. I was hesitant in the beginning because everyone complains about how it makes acne worse before it gets better. My advice to you is start out slowly and allow your skin to adjust. I started off with using it once a week..and gradually moved on to 3 times and I have not experienced purging.Also my skins pretty smooth and my scars are fading. Another thing…just use vaseline as a moisturizer…why should you bother your skin with extra chemicals? Also be wary of doctors who just hand you the retinol with no proper instructions. I researched extensively before buying the product and to my surprise the doctor couldn’t even advise that only a pea-size amount is to be used. Patience pays people 🙂

  13. 5 out of 5

    Sherita Xiong

    I developed whiteheads on my cheeks and had rather large pores on my nose with blackheads. I have been using the medication for a total of six months now. Initially, I had some redness, moderate peeling, and some slight burning right after applying the medication. After about three weeks, the side effects subsided and I started to notice my skin clearing, pore size minimizing, and an overall evening of complexion. I used Phisoderm Deep Cleansing face wash morning and night and then used Neutrogena Oil-free moisturizer with SPF 15 in the morning. My face is very oily so I did not experience much dryness.

  14. 3 out of 5

    Arletha Mathias

    Acne is gone! Thanx okdermo

  15. 5 out of 5

    Stephanie Blair

    Warning: Retin-A dries your skin out. I have found Cetaphil SPF 50 is the best moisturizer. Also, over time my skin has adjusted to the Retin-A and the dryness is not as dramatic.

  16. 4 out of 5

    Sanford Whitmire

    Thank you!

  17. 5 out of 5

    Elsie Garza

    Retin-A is a commitment. Your acne will more than likely get worse before it gets better and it WILL take 9 months- 12 months to really “work”.

  18. 4 out of 5

    Austin Mendoza

    I am on my 5 th week on tretinoin gel, to be honest definitely you need have patience.

  19. 5 out of 5

    Marylin Cowan

    May recommend

  20. 5 out of 5

    Sabrina Becker

    Using too much or using it too frequently will not make it work faster, in fact, it will do the exact opposite.. Trust me, I know this from experience. 🙂

  21. 5 out of 5

    Jovita German

    I have used Retin-A .01% Cream for acne for the past 20 years. I find it to be very therapeutic to my skin. Recently my doctor switched me to the gel and its incredible the way it feels. It is not tacky or greasy. Its a very greaseless lightweight gel. There is a little bit more alcohol in the gels than cream but overall it feels great on my skin and is keeping the Acne at bay. I highly recommend this gel, or even the creams for acne but you have to know how to use it. Speak to your doctor if you have any questions and do exactly what he says. Your skin needs to get used to the strongest strength of them all to treat the acne. Its a wonderful, wonderful product.

  22. 5 out of 5

    Lisa M.

    This is my favourite, the best of retinoic acids for its price and quality, greetings angela, thanks for support!

  23. 5 out of 5


    Totally best gel! That tretinoin gel is really working, i’m using it for my sun (against acne) and for my daily care routine against wrinkles and fine lines. thanks okdermo!

  24. 4 out of 5

    Rachell Smalls

    Retin A honestly changed my life!

  25. 4 out of 5

    Gail Keys

    My experience with Retin-A has been a life saver! I have used it for at least 20 years. It has helped with my acne problems over time… But it also helped soften & vanish much scarring. I was also amazed at how fast it would help my lesions heal. It was recommended to me years ago by a dermatologist along with an Aqua Glycolic face wash.

  26. 3 out of 5

    Alina Snell


  27. 5 out of 5

    Laurene Sewell

    I will continue to buy it… It saved my life!!

  28. 5 out of 5

    Bruce Santiago

    It’s a powerful treatment.

  29. 4 out of 5

    Irene Reyes

    effective skin treatment

  30. 5 out of 5

    Donna E.

    Ordered retinol, I have ordered from here once before and I was just as pleased then.

  31. 4 out of 5

    Dominga Bower

    I’ve been using Retin-A for about a week now. If you have oily skin or experience breakouts every morning like me, I would definitely recommend this. I use the .01% dosage recommended by my doctor. They told me I may experience peeling of the skin. My skin has peeled in some spots, but it’s not very noticeable. I removed the peeled skin by using baking soda and water(great exfoliant!) Skin varies by person. I’ve given up on every acne regimen and decided to see my doctor. I swear by this stuff. All my acne scars are fading and my skin has become significantly smoother.

  32. 5 out of 5

    Marilee Kroll

    I highly recommend this product to anyone suffering from acne! I started breaking out very badly and I was out on this cream by my dermatologist and I am so happy with the results its only been 5 days that I started using it and I am very happy with the results so far!

  33. 5 out of 5

    Marlana Matlock

    At first, you will most likely have your ugly-phase (flaky skin, break outs), don’t worry, just suck it up and get over yourself. It’ll pass! 🙂

  34. 5 out of 5

    Maye Oglesby

    I’ve dealt with moderate acne since I was roughly 12 years old. I’ve tried just about every acne treatment out there with no prevail. When I started my Retin-A (0.025) treatment 5 months ago I became really discouraged by my skins immediate discolouration, mostly red, and the flakiness it created. I came close a couple times to giving up, especially when my skin wasn’t clearing up and how sore I was some days from the continuous use. But this past month has been the turn around. I feel I am finally out of the so called ‘purge’ and my skin is becoming clear and smooth like it has been in past for short stints. The best advice I can give any user is to have patience. It’s not an overnight fix, but the long term results are worth it.

  35. 5 out of 5

    Marlene Day

    I’m on my second tube of 0.04 gel and nearly finished with it. Obviously I started out quite slowly, mostly due to fear from reading reviews. I think this has served me well, because I have experienced only ONE day where my chin peeled a very little bit.

  36. 5 out of 5

    Darrick Witt

    I have been using Retin-A along with the oral antibiotic Clindamycin for 4 months now. I am 20 and have had severe cystic acne since I was 11. I also had a lot of hyper-pigmentation and scarring, to the point where my face was always bright red and bumpy. In just 4 months my face has completely cleared up and smoothed out, it is visibly brighter. The hyperpigmentation is lightening significantly at this point, a few small pimples or blackheads occasionally but mostly clear! The only other product I use is witch hazel as a toner and an oil free moisturizer.

  37. 3 out of 5

    Sydney CItizen

    Qaulity retinol, thank you, working like a charm, packaged well, delivery was long 2.5 weeks to Perth but overall good experience

  38. 5 out of 5

    Rachal Battles

    I am a 72 year old woman who has been using Retin-A for thirty-four years. I started using it because I had adult acne at the same time my teenage son had acne. I routinely am mistaken for being twenty years younger than I am. I have very few wrinkles. My skin still has dry patches occasionally but they are short lived. I have tried to get several people to use it but they always get discouraged with the redness and peeling in the beginning. This phase does not last forever. Please continue to use it, you will never be sorry.

  39. 5 out of 5

    Rafaela Corbett

    I started using the .05% in the cream version. I used it for about 2 months using every other day and didn’t notice ANYTHING happening, not for good or bad. So, I upped my dosage to 1% in the gel version. Now, like I said, take it slow. I didn’t and I paid for it. I started using every day for the first 2 weeks. I was peeling.. All over.. Mouth, nose, eyebrows, eyes.. I couldn’t even smile without the corners of my mouth cracking open (and that shit takes forever to heal).

  40. 5 out of 5

    Amie Stpierre

    I’d been on Clinoxyl (benzoyl peroxide and clindamycin) for about 3 years before it stopped working very suddenly. Like, one day my skin was clear, and the next, I had breakouts on my chin and cheeks again. Anyway, I’d ordered a tube of 0.05% Retin-A online a while ago and used to use it as a spot treatment, which worked , for a bit. I think that was too strong for me. Just starting PRESCRIBED 0.04% Retin-A micro and, the morning after use on my entire face, my skin was less inflamed. I noticed 2 new pimples surfaced, but they were easily extracted. I use cetaphil gentle skin cleanser and then a toner + moisturizer in the mornings. Cetaphil cleanser – wait 20 mins – Retin-A – wait 20 mins – and neutrogena hydro boost moisturizer at night. I have noticed some blemishes come to the surface and minor peeling. But, my general skin tone looks so much better than when I was using the Acanya, despite those two drawbacks. Will keep using and see what the long-term results looks like!

  41. 5 out of 5

    Elfriede Mcdermott

    The first 6 months were awful. Hated my skin more by the day. But there is a huge silver light! Fast forward a few months and my skin is glowing, smooth, and hardly a single breakout.

  42. 4 out of 5

    Love the product

    Fast shipping just came today

  43. 5 out of 5

    Helene Hadden

    Super fast response time from website support

  44. 4 out of 5

    Bridgit Marchall

    The best one, 20g is enough for one month, very useful to maintain my skin in a perfect mood 🙂
    When .1% will be available again???

  45. 5 out of 5

    Alejandro Shelton

    For my skin (which is dry-to-sometimes very dry, sensitive, a d acne prone as well), I plan to just stick with using Retin A 0.1 Cream for helping to control my adult acne and for its added anti-aging benefits too.

  46. 5 out of 5

    Julia Russell

    I’m using RA because I’m almost in my 30’s, I want to prevent wrinkles, and boost collagen. I was starting to get little lines around my eyes and on my forehead. -I’m really expressive -hence my expression lines!

  47. 5 out of 5

    Helen D.

    This is a legit retinol product. Expiration more than a year!
    Highly recommend. Wonderful customer service and thank you for discounts

  48. 5 out of 5

    Allene Davison

    Working for me like a charm

  49. 4 out of 5

    Darius Booth

    I haven’t been using Micro long enough to give it a review on effectiveness, but I will say that switching from Tazarotene to Retin-A Micro has been a game changer for my skin. Tazorac/Tazret fried my face. It was red and irritated every day, which made it difficult to use products that help with acne control.

  50. 5 out of 5

    Round Bubble

    My order arrived in one week in UK WOW! thnx for reasonable prices

  51. 4 out of 5

    Lynn Hicks

    Retin-A is proven to increase your stores of collagen. And after using it for 2 and a half years now, my facial skin is firm and plump and *not saggy or droopy*. At all. It’s amazing at my age! You’ve gotta try it if you haven’t already!!

  52. 5 out of 5

    Brigette Fonseca

    Hey guys!! I started using retin-a 0.1% two years back but within a month my skin became very dry i stopped using it though there was no other side effects. But after reading comments here I got inspired and got courage to use it again. So I have started to use it again and hoping that it will work for me as well. I’ll leave an update my experience soon.

  53. 4 out of 5

    Craig Duncan

    As I live in a northern climate (Canada), the cold temperature and dry wind REALLY dries out my face even more while I’m on this treatment. Moisturizing and daily 60 SPF are a must. A weekly green clay mask seems to loosen the flakey top layers well.

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