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Nemocid® Pyrantel Tablets

Pyrantel Pamoate 250mg

USD $35.00

Brand:Ipca Labs

Pyrantel belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.

Pyrantel is used to treat pinworms (enterobiasis; oxyuriasis).

This medicine may also be used for other worm infections as determined by your doctor.

Pyrantel works by paralyzing the worms. They are then passed in the stool.

Size: 30 Tablets
Brand name: Ascarel, Pamix, Pinworm, Pin-X
Title Range Discount
Items: 2 - 4 5%
Items: 5 - 8 10%
Items: 9 + 15%

Description

Pyrantel is a medication used to treat several parasitic worm infections. This includes ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis. It is taken by mouth.

Nemocid® Pyrantel Tablet is an anti-helminthic medication. It is used in the treatment of worm infections. It works by killing the worms that cause infection. The killed worms are then passed in the stool.

Nemocid® Pyrantel Tablet should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

Some people may experience headache, dizziness, nausea, hair loss and vomiting, as the side effects of this medicine. Please consult your doctor if these side effects persist for a longer duration. You may be monitored with blood tests and liver function tests throughout your treatment.


Pyrantel: Overview

Pyrantel is a broad-spectrum anthelmintic (anti-parasitic) medication commonly used to treat intestinal worm infections. It is available in various forms, including tablets, chewable tablets, and oral suspension, making it suitable for both adults and children. Pyrantel is effective against multiple intestinal nematodes (roundworms), including pinworms, hookworms, and ascaris (roundworms).

Pyrantel works as a neuromuscular blocker, paralyzing worms and causing them to lose their grip on the intestinal walls. The paralyzed worms are then naturally expelled from the body through bowel movements without requiring additional laxatives.

Due to its safety profile and minimal systemic absorption, Pyrantel is widely used in humans, pets (dogs, cats), and livestock to treat parasitic infections.


On-Label Uses of Pyrantel (Approved Uses)

  1. Pinworm Infection (Enterobiasis – Caused by Enterobius vermicularis)
    • Pyrantel is an FDA-approved first-line treatment for pinworm infections.
    • It effectively paralyzes and expels the worms within a few days.
    • Often requires a second dose after 2 weeks to eliminate reinfections.
  2. Roundworm Infection (Ascariasis – Caused by Ascaris lumbricoides)
    • Pyrantel is highly effective against intestinal roundworms, one of the most common parasitic infections worldwide.
    • It helps clear the worms without significant gastrointestinal distress.
  3. Hookworm Infections
    • Treats Ancylostoma duodenale and Necator americanus, which can cause anemia due to blood loss.
    • By expelling the worms, Pyrantel prevents complications like nutritional deficiencies and chronic fatigue.
  4. Deworming in Pets (Dogs & Cats)
    • Used in veterinary medicine to treat hookworms, roundworms, and other intestinal parasites in animals.
    • Often combined with praziquantel or ivermectin for broader parasite coverage.

Off-Label Uses of Pyrantel

  1. Threadworm Infection (Strongyloidiasis – Caused by Strongyloides stercoralis)
    • Though not a first-line treatment, Pyrantel is sometimes used in cases where other medications (e.g., ivermectin) are unavailable.
  2. Whipworm Infection (Trichuriasis – Caused by Trichuris trichiura)
    • In some cases, Pyrantel may be used in combination with other anthelmintic drugs like albendazole for better efficacy.
  3. Preventative Deworming in High-Risk Areas
    • Used in regions with high rates of parasitic infections to prevent reinfections in communities.
    • Often included in mass deworming programs for children in endemic areas.
  4. Use in Livestock and Farm Animals
    • Used in cattle, sheep, goats, pigs, and horses to treat intestinal nematode infestations.

Why Pyrantel is Beneficial

Broad-Spectrum Activity – Effective against multiple types of intestinal worms.
Minimal Absorption – Acts locally in the intestines, reducing side effects.
Single-Dose Treatment – Convenient and effective in most cases.
Safe for All Ages – Approved for children over 6 months and adults.
Veterinary Uses – Helps keep pets and livestock healthy by eliminating parasites.


Precautions & Warnings

1. Contraindications

  • Hypersensitivity: Do not use if allergic to Pyrantel or any of its ingredients.
  • Severe Liver Disease: Use with caution in individuals with liver dysfunction, as metabolism may be affected.
  • Pregnancy & Breastfeeding: Generally considered safe, but consult a doctor before use.

2. Warnings & Precautions

  • Gastrointestinal Effects: May cause mild nausea, vomiting, abdominal cramps, or diarrhea.
  • Neurological Side Effects (Rare): Dizziness, drowsiness, or headaches may occur.
  • Possible Reinfection:
    • Good hygiene practices (e.g., frequent handwashing, washing bedding/clothes) are crucial to prevent reinfection, especially for pinworms.
    • Family members may also need treatment to prevent the spread.
  • Interactions with Other Medications:
    • Do NOT use with piperazine (another deworming agent), as it may reduce Pyrantel’s effectiveness.
    • Consult a healthcare provider if taking theophylline (for asthma), antacids, or laxatives, as they may interact.

Frequently Asked Questions (FAQ)

1. How does Pyrantel work?

Pyrantel paralyzes intestinal worms by acting on their neuromuscular system. The paralyzed worms are then expelled naturally in stool without causing discomfort.

2. How should Pyrantel be taken?

  • For pinworms: A single dose is usually sufficient, but a second dose after 2 weeks is recommended to prevent reinfection.
  • For roundworms or hookworms: A single dose or a short course (2-3 days) is often needed.
  • It can be taken with or without food, but chewing or crushing the tablet before swallowing enhances absorption.

3. How quickly does Pyrantel work?

  • Worms typically begin to be expelled within 24 hours of taking the medication.
  • Full elimination may take a few days to a week.

4. Can Pyrantel be used in young children?

Yes! Pyrantel is approved for children older than 6 months. However, the dosage is weight-dependent, so consult a doctor for proper dosing.

5. What are the side effects of Pyrantel?

Common side effects include:

  • Mild stomach discomfort (nausea, vomiting, cramps)
  • Dizziness or headache (rare)
  • Diarrhea (infrequent)

Most side effects are temporary and resolve on their own.

6. Is Pyrantel available over the counter (OTC)?

Yes, in many countries, Pyrantel is available OTC for treating pinworms and roundworms. However, for other infections, a doctor’s prescription may be required.

7. Does Pyrantel kill all parasites?

No. Pyrantel is effective against roundworms, hookworms, and pinworms, but it does not work for:

  • Tapeworms (Praziquantel or Niclosamide is preferred)
  • Whipworms (Albendazole or Mebendazole is preferred)

8. Can I take Pyrantel while pregnant or breastfeeding?

  • Pyrantel is classified as safe during pregnancy (Category C) but should be used only if benefits outweigh risks.
  • Minimal amounts pass into breast milk, so it is generally considered safe while breastfeeding.

9. Do I need to take Pyrantel again after the first dose?

  • For pinworms: A second dose after 2 weeks is usually recommended.
  • For other infections: One dose may be enough, but severe infections may require multiple treatments.

10. Can Pyrantel be used for pets?

Yes! Pyrantel is commonly used for dogs, cats, and farm animals to treat roundworms and hookworms. It is often combined with other dewormers for complete parasite control.


Conclusion

Pyrantel is a highly effective, safe, and widely available deworming medication for humans and animals. With its broad spectrum of activity, minimal side effects, and single-dose effectiveness, it is a preferred treatment for pinworms, roundworms, and hookworms. Its potential preventative use in high-risk areas and veterinary applications further highlight its importance in public health and animal care.

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