What is Methoxsalen 1% USP Topical Solution Generic Oxsoralen® | Melanocyl®
Methoxsalen (also called xanthotoxin, marketed under the trade names Oxsoralen, Deltasoralen, Meladinine) is a drug used to treat psoriasis, eczema, vitiligo, and some cutaneous lymphomas in conjunction with exposing the skin to UVA light from lamps or sunlight. Methoxsalen modifies the way skin cells receive the UVA radiation, allegedly clearing up the disease. Levels of individual patient PUVA exposure were originally determined using the Fitzpatrick scale. Chemically, methoxsalen belongs to a class of organic natural molecules known as furanocoumarins. They consist of coumarin annulated with furan. It can also be used topically as a solution or ointment or orally if comes in tablet form.
Methoxsalen belongs to the group of medicines called psoralens. It is used along with ultraviolet light (found in sunlight and some special lamps) in a treatment called PUVA to treat vitiligo, a disease in which skin color is lost, and psoriasis, a skin condition associated with red and scaly patches. Methoxsalen is also used with ultraviolet light in the treatment of white blood cells. This treatment is called photopheresis and is used to treat the skin problems associated with mycosis fungoides, which is a type of lymphoma. Methoxsalen may also be used for other conditions as determined by your doctor.
Melanocyl Solution is a psoralen, which is used in combination with light therapy. Melanocyl Solution works by making the skin more sensitive to UV light. Melanocyl Solution appears that this sensitivity results in damage to the skin cells when UV light treatment is given. Damaged skin cells grow more slowly and the rate of tissue growth is reduced.
Brand Name: 8-Mop, Oxsoralen-Ultra
How to use Methoxsalen 1% USP Topical Solution Melanocyl®
Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Melanocyl Solution is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
- Wear UVA-absorbing, wrap-around sunglasses and cover exposed skin or use a sunblock (SP 15 or higher) for the twenty-four (24) hour period following treatment with methoxsalen topical.
- Use extra caution for at least 48 hours following each treatment. After each treatment, cover your skin for at least 8 hours by wearing protective clothing.
- Do not increase the amount of methoxsalen topical if you are taking or spending extra time in the sunlight or under an ultraviolet lamp.
- You may have to undergo an eye examination before starting the treatment and also once a year thereafter.
- Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
- Do not use if you are allergic to methoxsalen or any of its ingredients.
- Do not use by children < 12 years.
- Do not use if you have a history of light-sensitive conditions (e.g., albinism, lupus, porphyria, xeroderma pigmentosum).
- Do not use if you having aphakia (no lens in the eye).
- Do not use if you have a history of melanoma or certain other types of skin cancer.
How Methoxsalen 1% USP Topical Solution Melanocyl® works
Melanocyl Solution is an organic compound. It is applied to the skin along with ultraviolet-A irradiation. It works by decreasing the number of cells the skin makes.