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Melaglow® Skin Lightening Cream

Avobenzone 0.05% + Soya Isoflavonoids 0.1% + Glabridin 0.05% + Tetrahydro Curcuminoid 0.05%

(3 customer reviews)

From USD $27.00


Melaglow is a potent but natural skin lightening/brightening cream, usually prescribed for the treatment of hyper-pigmentation of skin and lightening the complexion of facial skin.

The cream is effective against hyper-pigmentation, reduce brown spots, makes the skin firmer, re-activates the skin cells for reduction of spots, suitable for all skin types, improves the overall look of the skin.

Melaglow cream contains a potent combination of soy isoflavones, licorice extract, Tetrahydro curcumin, avobenzone. Melaglow skin brightening/lightening cream is used in cases of hyperpigmentation and dark spots and to brighten darker patches on the skin, under the eye, neck, etc.

Melaglow cream makes the skin firmer and re-activates the skin cells for reduction of spots, can also be used on pimple marks, and can be used on all skin types.

Size: 30g / 1.05oz
Title Range Discount
Items: 2 - 4 5%
Items: 5 - 8 10%
Items: 9 + 15%



Melaglow cream is the brand name for a strong natural skin lightening and brightening cream, usually prescribed for the treatment of hyper-pigmentation of skin and lightening the complexion of skin. The active ingredients present in Melaglow skin lightening cream and their composition is the following:


Avobenzone was introduced in the 1990s and is a common chemical sunscreen component. Unlike other chemical sunscreens that just protect from the sunburn-causing UVB rays, avobenzone also protects from UVA rays, the rays that cause premature aging and skin cancer. Avobenzone is a hydroquinone derivative sun-screening chemical. It works by discoloring spots and freckles on skin. It also prevents the spots caused by exposure to ultraviolet rays. Hydroquinone has a reversible depigmentation effect on the skin. The accumulation of melanin, the skin pigment which causes skin darkening, is reduced by its bleaching effect. The synthesis of Melanin along with some important processes which result in the formation of Melanin inside the cells get inhibited by hydroquinone.

Soya Isoflavonoids (Genistein and Daidzein) is a plant chemical, similar to female hormone estrogen. It helps in rejuvenating new skin cells. Soya Isoflavonoid is a compound found in a wide variety of foods, but mostly soy, that affect a wide-variety of body systems. They seem to mimic the female hormone estrogen to a degree (although slightly different). They generally are good at cardioprotection from reducing lipoprotein levels and are seen as good for bone health in the aging as well. Isoflavonoids is a natural skin bleaching ingredient which blocking the skin pigment cells melanocytes.

Glabridin is also an isoflavonoid, it is a chemical compound that is found in the root extract of licorice (Glycyrrhiza glabra). Glabridin is an isoflavane, a type of isoflavonoid. This product is part of a larger family of plant-derived molecules, the natural phenols. Glabridin inhibits tyrosinase activity of these cells at concentrations of 0.1 to 1.0 microg/ml and had no detectable effect on their DNA synthesis. Combined analysis of SDS-polyacrylamide gel electrophoresis and DOPA staining on the large granule fraction of these cells disclosed that glabridin decreased specifically the activities of T1 and T3 tyrosinase isozymes. It was also shown that UVB-induced pigmentation and erythema in the skins of guinea pigs were inhibited by topical applications of 0.5% glabridin. Anti-inflammatory effects of glabridin in vitro were also shown by its inhibition of superoxide anion productions and cyclooxygenase activities. These data indicated that glabridin is a unique compound possessing more than one function; not only the inhibition of melanogenesis but also the inhibition of inflammation in the skins. By replacing each of hydroxyl groups of glabridin with others, it was revealed that the inhibitory effect of 2′-O-ethyl glabridin was significantly stronger than that of 4′-O-ethyl-glabridin on melanin synthesis in cultured B16 cells at the concentration of 1.0 mg/ml. With replacement of both of two hydroxyl groups, the inhibitory effect was totally lost. Based on these data, we concluded that two hydroxyl groups of glabridin are important for the inhibition of melanin synthesis and that the hydroxyl group at the 4′ position of this compound is more closely related to melanin synthesis.

Tetrahydro Curcuminoid has anti-inflammatory and antioxidant properties. It helps in reducing the pigmentation. Tetrahydro Curcuminoid is used for Antioxidant action, Anti-inflammatory action, Skin-lightening action, Free radical formation prevention and other conditions. This salt may also be used for purposes not listed in this description. This ingredient has superior skin-whitening abilities. Tetrahydrocurcumin was shown to result “in the significant neutralization of free radicals,” and yielded better results than other compounds in the tested group. It also had the strongest antioxidant activity among all curcuminoids, and showed anti-inflammatory potential.


Melaglow skin cream is administered in the prevention, control and treatment of following skin topical conditions:

  • Ultra violet rays protection, diabetes and breast cancer
  • Lactose intolerance, kidney disease in people with diabetes
  • Diarrhea, hereditary lactase deficiency, galactosemia
  • Kidney disease, high cholesterol
  • Menopausal symptoms, osteoporosis
  • Skin-lightening and free radical formation prevention


There are no studies conducted to prove the effectiveness or efficacy of Melaglow for skin lightening and anti-ageing , but the claimed individual ingredients can be quite effective in pigmentation reduction, skin cells rejuvenation and protection against inflammation (which causes wrinkles and freckles and thus ageing of skin). Consult a dermatologist before using this cream to know if you can use it.


Some common side-effects of generic components of Melaglow cream may appear: skin redness due to allergic reaction,  itching, soreness, mild skin irritation, inflammation, burning, erythema & stinging, changes in color of skin, burning, acne, dryness in the skin, stinging, facial swelling, blisters at the cream applied area, darkening of the color of the skin , thickening of the skin, tenderness in the skin, scaling and mild burning, reaction at the cream applied area.


The quantity of Melaglow cream to be applied for the particular skin condition and also the frequency of application per day has to be as per dermatologist’s prescription. Also, one must not exceed the duration (in terms of number of days) of the use of this cream.

Following precautions are suggested for the use of this cream: don’t use for long time (more than six months), tell your dermatologist if you have any skin disease or skin condition, especially eczema and psoriasis. Tell your dermatologist if you are taking any medicine and if you are currently applying any other topical cream. Do not use if allergic to any of the ingredients. It is strictly advised to consult a dermatologist before using this cream to ensure that it is well suited for your skin. For topical application this medicine is relatively safe to use during pregnancy. But it should be used only if clearly needed. Melaglow belongs to pregnancy category ‘N’, FDA has not yet classified the topical drug into a specified pregnancy category. Consult a doctor to know if this cream is safe for you. Melaglow cream is available as an over the counter (OTC) product in skin care store. But it is suggested that you consult a dermatologist to know if you can use this medicine on your skin.

Additional Information


  • Avobenzone 0.05% w/w
  • Soya isoflavonoids 0.1% w/w
  • Glabridin 0.05% w/v
  • Tetrahydro curcuminoid 0.05% w/w