What is L-Arginine + L-Citrulline Supplement?
There are many nutrients that your body relies on that it can’t produce itself, such as essential amino acids. L-arginine and L-Citrulline are essential amino acids that your body uses to build proteins, and it’s found in foods like turkey and pumpkin seeds. In supplement form, the L-arginine + L-Citrulline combo works to dilate blood vessels, which can benefit cardiovascular health, fuel workouts, and help with erectile dysfunction.
L-Arginine + L-Citrulline may facilitate aid for the symptoms of mild-to-moderate erectile dysfunction. It enhances muscle protein levels in the body and prevents malnourishment in the elderly. L-Arginine is a non-essential amino acid. It works as a vasodilator that widens blood vessels and improves blood flow hence reducing blood pressure and erectile dysfunction conditions of the body. It also stimulates the release of growth hormone, insulin, and improves immunity. L-citrulline aids to overcome fatigue, muscle weakness, and enhances the athletic performance of the body.
L-Arginine + L-Citrulline supplement helps in cell growth and maintenance. It is useful in performing normal body functions, make up the deficiencies in the body, and protecting cells from wear and tear. Helps to reduce the risk of cardiovascular diseases, helps to improve blood circulation, may help to regulate the blood pressure level. L-arginine is a nonessential amino acid that may play an important role in the treatment of cardiovascular disease due to its anti-ischemic, antiplatelet, and antithrombotic properties. L-citrulline is a non-essential amino acid changed into another amino acid called L-arginine and a chemical called nitric oxide. These compounds are important to your heart and blood vessel health. They may also boost your immune system. Higher nitric oxide levels relax and dilate blood vessels, thus increasing blood circulation to various organs, including the heart, skin, and sexual organs.
L-citrulline is a substance called a non-essential amino acid. Your kidneys change L-citrulline into another amino acid called L-arginine and a chemical called nitric oxide. These compounds are important to your heart and blood vessel health. They may also boost your immune system. All your cells use ATP molecules for energy. Your muscles use ATP for energy and in turn, produce IMP (inosine monophosphate, a nucleoside), lactic acid, and ammonia. These byproducts of exercise accumulate and cause muscle fatigue. l-Citrulline supports muscle recovery after exercise, helping clear ammonia from the liver and converting it to urea for excretion. This enables the muscles to recover after exercise.
l-Arginine is an amino acid, important in muscle metabolism and the formation of nitric oxide (NO) in the body. The formation of nitric oxide (NO) regulates smooth muscle relaxation in the blood vessel wall and reduces the workload of the heart. l-Arginine and l-Citrulline supports a healthy cardiovascular-metabolic system primed for action and workout recovery.
We’ve combined these two amino acids to provide a more convenient performance-enhancing product for athletes. During intense exercise, there is an increased production of ammonia in the exercised muscle. l-Arginine & l-Citrulline from Mega ED supports metabolism, protein synthesis, and liver detoxification. The l-arginine supports nitric oxide (NO) production, beneficial to the heart and blood vessels, while the l-citrulline supports detoxification of ATP metabolism byproducts beneficial for post-workout recovery.
Benefits of L-Arginine
L-arginine converts into nitric oxide in the body, which expands blood vessels and allows for proper blood flow. Doctors recommend arginine supplements to patients with certain heart conditions, like coronary heart disease, clogged arteries, and angina. Increased circulation also makes L-arginine supplements popular with men with erectile dysfunction (ED), and even low libido. Lastly, these supplements are popular with weightlifters and athletes because they allow for more oxygen to reach the lungs.
L-arginine is a chemical building block called “an amino acid.” It is obtained from the diet and is necessary for the body to make proteins. L-arginine is found in red meat, poultry, fish, and dairy products. It can also be made in a laboratory and used as medicine. L-arginine is used for heart and blood vessel conditions including congestive heart failure (CHF), chest pain, high blood pressure, high cholesterol, heart surgery, recovery after a heart transplant, heart attack, and coronary artery disease. L-arginine is also used for recurrent pain in the legs due to blocked arteries (intermittent claudication), decreased mental capacity in the elderly (senile dementia), erectile dysfunction (ED), altitude sickness, nitrate tolerance, diabetes, diabetic nerve pain, kidney toxicity from cyclosporine, kidney disease, tuberculosis, critical illness, head and neck cancer, obesity, ovary disease (polycystic ovary syndrome), pressure ulcers, respiratory infections, sickle cell disease, stress, and male infertility.
Some people use L-arginine for preventing the common cold, improving kidney function after a kidney transplant, high blood pressure during pregnancy (pre-eclampsia), improving athletic performance, boosting the immune system, and preventing inflammation and tissue death of the digestive tract in premature infants (necrotizing enterocolitis) and preventing slowing of the growth of the baby within the uterus.
L-arginine is used in combination with a number of over-the-counter and prescription medications for various conditions. For example, L-arginine is used along with ibuprofen for migraine headaches; with conventional chemotherapy drugs for treating breast cancer; with other amino acids for treating weight loss in people with AIDS; and with fish oil and other supplements for reducing infections, improving wound healing, and shortening recovery time after surgery. Some people apply L-arginine to the skin to speed wound healing, healing of small rips of the anus, and for increasing blood flow to cold hands and feet, especially in people with diabetes. It is also used as a cream or supplement for sexual problems in both men and women. Arginine has also been used for dental caries and dental hypersensitivity.
Finally, arginine has been injected into the vein for recurrent pain in the legs due to blocked arteries (intermittent claudication), reduced blood flow to the limbs (peripheral artery disease), for detecting growth hormone deficiency, disease due to defective mitochondria (mitochondrial encephalomyopathies), chest pain due to gastric problems, restenosis, kidney transplant, nutrition for the critically ill, metabolic acidosis, and increased blood pressure in the artery of the lungs (pulmonary hypertension) in newborns.
L-Arginine is effective for:
- Chest pain (angina). Taking L-arginine seems to decrease symptoms and improve exercise tolerance and quality of life in people with angina. However, L-arginine does not seem to help widen the blood vessels that are narrowed in angina.
- Erectile dysfunction (ED). Taking 5 grams of L-arginine by mouth daily seems to improve sexual function in men with ED. Taking lower doses might not be effective. However, there is some early evidence that taking L-arginine with maritime pine bark extract and other ingredients, might improve the effectiveness of low-dose L-arginine for ED.
- High blood pressure. There is early evidence that taking L-arginine by mouth can reduce blood pressure in healthy people, people with high blood pressure, and people with slightly high blood pressure with or without diabetes.
- Inflammation and tissue death in the digestive tract in premature infants (necrotizing enterocolitis). Adding L-arginine to formula seems to prevent inflammation of the digestive tract in premature infants. A total of 5 premature infants need to receive arginine to prevent one instance of digestive tract inflammation.
- Nitrate tolerance. Taking L-arginine by mouth seems to prevent nitrate tolerance in people taking nitroglycerin for chest pain (angina pectoris).
- Leg pain associated with poor blood flow (peripheral arterial disease). Research suggests that taking L-arginine by mouth or intravenously (by IV) for up to 8 weeks increases blood flow in people with peripheral arterial disease. However, long-term use (up to 6 months) does not improve walking speed or distance in people with peripheral arterial disease.
- Improving recovery after surgery. Taking L-arginine with ribonucleic acid (RNA) and eicosapentaenoic acid (EPA) before surgery or afterward seems to help reduce the recovery time, reduce the number of infections, and improve wound healing after surgery.
- High blood pressure during pregnancy (pre-eclampsia). Most research shows that L-arginine can reduce blood pressure in women with this condition. L-arginine might also prevent this condition in pregnant women.
Benefits of L-Citrulline
L-citrulline is a substance called a non-essential amino acid. Your kidneys change L-citrulline into another amino acid called L-arginine and a chemical called nitric oxide. These compounds are important to your heart and blood vessel health. They may also boost your immune system.
L-citrulline boosts nitric oxide production in the body. Nitric oxide helps your arteries relax and work better, which improves blood flow throughout your body. This may be helpful for treating or preventing some diseases. There is some evidence to suggest the supplement could possibly help lower blood pressure in people with prehypertension. This is an early warning sign for high blood pressure. It means you have a slightly raised blood pressure reading of 120/80 to 139/89. Prehypertension raises your risk for high blood pressure and heart disease. L-citrulline supplements may ease symptoms of mild-to-moderate erectile dysfunction (ED). Scientists say L-citrulline does not work as well as ED drugs such as Viagra. However, it appears to be a safe option.
Always tell your doctor about any supplements you are taking. That way, your doctor can check on any potential side effects or interactions with any medications.