What is Innotox® Liquid Solution?
To temporarily improve moderate to severe glabellar wrinkles related to eyebrow wrinkle muscle (corrugator muscle) and/or procerus muscle activity in adults aged from 20 to 65. Innotox Liquid Type A Complex is South Korean (KFDA) innovative product for smoothing mimic wrinkles on the face. This liquid form is popular in many countries thanks to the ease of use and long-lasting result.
Innotox is completely ready for use, no need to mix with saline water. It has a low degree of diffusion prevents the influence of toxin on the tissues adjacent to the correction area. This product is not temperature sensitive and is stable up to 82 degrees. The result of the procedure lasts up to 8 months.
Unlike other botulinum toxins, Innotox can be stored and transported at room temperature, it is heat resistant up to 28 degrees Celsius, 82 Fahrenheit. Recommended storing in the fridge if not in immediate use for longer shelf life. The open vial can be stored in the fridge for up to two weeks.
The product is manufactured by Medytox Inc. in the form of a solution in vials, one in a package. The basic component is botulotoxin type A Clostridium botulinum in the amount of 50 or 100 units.
Innotox is predicted by the same Hall strain of C.botulinum as Neuronox and Botox. The molecular weight of Innotox analyzed using size-exclusion SE-HPLC is approximately 900 kDa. Which is highly comparable to those of Neuronox and Glowtox.
Another key characteristic of Innotox is that it excludes the use of substances of animal origin in the manufacturing process to eliminate the risks associated with animal-based proteins. Moreover, it excludes human serum albumin as an excipient of the final product to avoid any risk associated with diseases of human blood origin. Instead, it contains methionine and polysorbate as a stabilizer.
The safety and efficacy of Innotox and Glowtox were compared at a 1:1 dose ratio for treating glabellar lines in a double-blinded, randomized, phase III multi-center study with 168 subjects. The patients, aged 20 to 65 years with moderate-to-severe glabellar lines, were randomly treated with 20U of Innotox or Glowtox and subsequently assessed by blinded investigators. The improvement rate at both maximum frown and rest was not significantly different between the Innotox and Glowtox groups. No severe adverse drug reactions were observed.
How to use Innotox® Liquid Solution
This product can be used for micro/nano needling such as the Hydra Stamp 20pin, Hydra Roller 64pin, or Hydra Pen. This product is recommended for use with MesoGlow Soft Cones 0.6mm. It can also be used as a cocktail with another micro/nano needling serums. Results take 7-14 days after each treatment. Allow 2 weeks between each treatment.
Indications of Innotox® Liquid Solution
- Innotox is indicated for the treatment of benign essential blepharospasm in patients 18 years of age and above.
- Innotox is indicated for the treatment of equinus foot deformity due to spasticity in pediatric cerebral palsy patients 2 years of age and above.
- Innotox® is intended for eliminating wrinkles caused by the spasticity of muscles or active mimics. It removes lines and folds in the areas of the eyes, between the eyebrows, forehead, around the mouth.
- Mimic wrinkles;
- Excessive sweating of palms and armpits (hyperhidrosis)