Description
Glycolic acid is the smallest α-hydroxy acid (AHA), renowned for its superior ability to penetrate the stratum corneum and dissolve intercellular “glue” that binds dead keratinocytes together. At a 6 % concentration—clinically documented as effective yet well-tolerated—this cream exfoliates superficially to reveal smoother, more even skin without excessive irritation^1. By removing dull surface cells and stimulating collagen synthesis, it addresses both cosmetic and structural concerns in a single step.
Key Ingredients and Mechanism of Action
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Glycolic Acid (6 %): Accelerates desquamation by cleaving corneocyte bonds, improving hydration, texture, and luminosity Journal of Cosmetic Dermatology.
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pH-Buffered Base: Maintains an optimal pH (~3.8) to maximize acid efficacy while reducing irritation Dermatologic Surgery.
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Glycerin & Sodium PCA: Potent humectants that restore moisture lost during exfoliation, supporting barrier repair International Journal of Cosmetic Science.
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Panthenol & Allantoin: Soothing agents that calm potential sensitivity, enhancing tolerability for medium-strength peels.
Benefits and Clinical Applications
Exfoliation & Cell Turnover
By loosening corneocyte attachments, Glycolic 6 Cream accelerates epidermal renewal, resulting in:
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Brighter, more uniform tone through accelerated sloughing of pigmented cells British Journal of Dermatology.
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Reduction of rough texture and hyperkeratosis, improving skin smoothness within two to four weeks.
Anti-Aging & Collagen Stimulation
Superficial exfoliation triggers dermal remodeling:
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Stimulates fibroblast activity to boost collagen and elastin synthesis, reducing fine lines and wrinkles Clinical, Cosmetic and Investigational Dermatology.
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Improves skin firmness and elasticity over continued use.
Pigmentation Control
Ideal for:
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Melasma & Hyperpigmentation: Disrupts melanosome transfer to keratinocytes, promoting faster fading of dark spots.
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Post-Inflammatory Hyperpigmentation (PIH): Effective in evening tone after acne lesions heal Journal of Drugs in Dermatology.
Acne & Scar Management
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Sebum Regulation: Glycolic acid reduces follicular occlusion, minimizing blackheads and whiteheads Journal of Cosmetic Dermatology.
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Acne Scars & Scarring: By promoting dermal remodeling and resurfacing, it softens atrophic scars and improves overall texture.
Who Should Use Glycolic 6 Cream?
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Normal/Combination Skin: Balanced formulation hydrates without over-drying.
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Oily/Acneic Complexions: Medium strength reduces sebum build-up and congestion.
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Aging & Photo-Aged Skin: Addresses fine lines, wrinkles, and sun damage.
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Hyperpigmentation Concerns: Targets melasma, age spots, and dark discolorations.
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Acne-Prone & Scarred Skin: Smooths texture and lightens post-inflammatory marks.
Usage Guidelines
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Cleanse: Start with a gentle, non-exfoliating cleanser.
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Apply: Dispense a pea-sized amount, spreading evenly over face avoiding eye area.
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Frequency: Begin twice weekly, gradually increasing to nightly as tolerated.
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Sunscreen: Mandatory daily application of SPF 30+ to prevent UV-induced irritation and pigmentation rebound^2.
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Moisturize: Follow with a calming moisturizer to offset potential dryness.
Science-Backed Safety Profile
Medium-strength glycolic peels (4–10 %) have been validated for both efficacy and safety when formulated with buffering agents and hydrating boosters^3. Adverse effects—such as transient redness or mild peeling—are typically self-limiting and can be mitigated by starting with lower frequency and applying barrier-supportive ingredients.
Novel Insights & Advanced Considerations
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Encapsulated Delivery Systems: Emerging formulations use liposomal encapsulation to further minimize irritation while enhancing penetration—a frontier for next-gen glycolic therapies.
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Synergistic Combinations: Blending 6 % glycolic acid with niacinamide or tranexamic acid can amplify depigmenting effects while supporting barrier function Dermatology and Therapy.
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Chronotherapeutic Application: Evening use aligns with nocturnal skin repair cycles, optimizing collagen synthesis and minimizing phototoxicity risk.
Why Choose Glycolic 6 Cream at ExfoliateShop.com?
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Pharmaceutical-Grade Quality: Manufactured under strict GMP guidelines to ensure consistent acidity, stability, and bioavailability.
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Transparent Formulation: Full disclosure of all actives and humectants, with no hidden irritants or fragrances.
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Backed by Research: Each ingredient is selected for evidence-based efficacy and tolerability, reflecting our commitment to scientifically grounded skincare.
FAQ
How often should I use Glycolic 6 Cream?
Start with two applications per week, gradually increasing to nightly use as tolerated. Always follow with SPF 30+ during the day.
Can I use this cream if I have sensitive skin?
Yes—begin with reduced frequency, apply on damp skin, and pair with a gentle moisturizer to minimize irritation.
Will Glycolic 6 Cream help with acne scars?
By promoting dermal remodeling and resurfacing, it can soften atrophic scars and improve overall skin texture.
Is sun protection necessary when using this product?
Absolutely. Glycolic acid increases sun sensitivity; daily broad-spectrum SPF 30+ is mandatory.
