Flonida® Fluorouracil Cream

Fluorouracil 1% / 5%

4.40 out of 5

(5 customer reviews)

From USD $22.00 (EUR €23.21)


Fluorouracil is used on the skin to treat pre-cancerous and cancerous skin growths. Fluorouracil belongs to anti-metabolites.

Flonida works by blocking the growth of abnormal cells that cause the skin condition.

Always consult your dermatologist prior to using/purchasing Fluorouracil cream.

Size: 10g / 0.35oz
Brand name: Efudex, Carac, Fluoroplex, Tolak
Title Range Discount
Items: 2 - 4 5%
Items: 5 - 8 10%
Items: 9 + 15%


What is Fluorouracil 1%-5% cream

Flonida Fluorouracil 1%-5% cream made by famous Menarini with all over the world presence. Fluorouracil 1%-5% cream works by interfering with the growth of skin cells to kill abnormal skin cells but will not harm normal cells. High-quality generic to Adrucil and Efudex creams.

The main active ingredient of Flonida cream is fluorouracil is considered an antimetabolites type of component that destroys cancer cells and cells which may become cancerous. Flonida Fluorouracil cream widely used in calming such conditions like eczema, psoriasis, and dermatitis. Flonida Fluorouracil cream is also flawlessly used in the treatment of solar or actinic keratoses, a skin condition where years of exposure to UV sunlight rays can cause scaly or crusted skin areas.

Fluorouracil 1%-5% cream is a topical treatment for several types of skin lesion both pre-malignant and malignant. Fluorouracil cream is used to treat actinic keratosis (also known as solar keratosis), a pre-malignant skin lesion characterized by thick raised scaly patches of skin caused by too much exposure to the sun. This is usually found in fair-skinned people on exposed parts of the body; when associated with aging this is known as senile keratosis. Keratosis refers to the overproduction of keratin, which is a fibrous structural protein in the outer skin layers (epidermis) and can also be caused by arsenic, a natural mineral used in industrial or agricultural compounds (arsenical keratosis); this form of keratosis can be found on the palms of the hands of soles of the feet.

If left untreated keratosis can develop into squamous cell carcinoma (SCC), which is a non-melanoma type of malignant skin cancer. Fluorouracil 1%-5% cream is also used to treat basal cell carcinoma (BCC), which is the most common form of skin cancer and although it is malignant (invasive) it is not usually harmful. BCC develops in the basal layer of the epidermis, is found mainly on the head, neck and other exposed areas in skin of fair-skinned people and is caused by excess sun exposure or repeated sunburn. BCC grows slowly and varies in appearance from small translucent nodules to larger brown, reddened or thickened patches of skin and can form ulcers and bleed easily.

Keratoacanthoma is a form of skin cancer that develops from a hair follicle and can be triggered by sun exposure or a minor injury; it appears as a dome-shaped nodule on the skin. These lesions respond to treatment with Fluorouracil cream whereas SCC does not because although it develops from the epidermis it grows down into the deeper skin layers (dermis). Fluorouracil Cream is only used for SCC when no other treatment is possible. Fluorouracil cream is also used to treat Bowen’s disease, which is thought to be an early form of SCC and develops from the epithelium beneath the epidermis. It can occur anywhere on the skin, where it appears as a patch of reddened crusty and scaly skin.

How to use Fluorouracil 1%-5% cream | Efudex generic

Read the patient information leaflet provided by your doctor/dermatologist/pharmacist before you start using this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Always consult your doctor prior to using/purchasing Fluorouracil cream.

Use this medicated cream as directed by your doctor. Before you apply this medication to the skin, clean the affected area and dry well. Wait 10 minutes, then apply a small amount of medication to the affected skin, using just enough to cover the area with a very thin film. Wash your hands immediately after applying this medication, even if you have used gloves.

The treated area may become unsightly during treatment and in some cases for several weeks after treatment. Do not cover the area with tight dressings or plastic bandages. Check with your doctor whether you may cover the treated area loosely with gauze. Avoid applying this medication in or around the eyes or eyelids. Also, do not apply this medication inside the nose or mouth. If you do get the medication in these areas, rinse with plenty of water.

Use this medicated cream exactly as prescribed. Do not stop using this medication without consulting your doctor. Do not increase your dose or use it more often than directed. Your condition will not clear faster, but side effects will be increased. If your condition worsens or does not improve, consult your doctor promptly.

Flonida Fluorouracil cream may cause unwanted side effects such as eye irritation, skin discoloration, photosensitivity, swelling and inflammation of the skin, dry, flaking or peeling skin, irritation, burning or redness at the application site.

What conditions does Fluorouracil 1%-5% cream teat?

Additional Information


5 reviews for Flonida® Fluorouracil Cream

  1. 4 out of 5

    Anja Didewson

    Being a white Aussie girl who loved being outside my skin was a mess. I’m now 58. I’ve used Efudex/(now Flonida) several years ago with great success. Started again due to scaley patches on the face that never went away. These reacted instantly and then disappeared. After having a break started using pigmentations on my face. These too reacted, interestingly I started getting reactions on places I didn’t put the cream. So I started putting the cream there too. My face is a mess, very itchy, sore. I certainly wouldn’t recommend using this on large areas at a time due to the uncomfortableness of the process. I know it will be worth it, so I will continue on. I have some lumps on my head, once my face is done I will be doing my scalp

  2. 4 out of 5


    Two weeks after flonida cream and my skin looked incredible – soft and everyone asked if I got a peel! 1 day later day 15 there was burn abrasions, raised cuts and I went to my scheduled two week check in with dr and she said it’s “working Beautifully” and continue for two more weeks.

    During week 3 I had small “cuts” all over my face where I applied cream 2x a day. Small scabby cuts also appeared on my scalp, chest even though I didn’t apply the medication there. The dr said that was strange, but I read in the leaflet it’s plausible.

    Horrible taste in mouth and sick to my stomach within 20 min of applying still. I’m in horrible pain, look awful and two more weeks to go. Had SCC with two Mohs surgery then reconstruction of Nose and head earlier last year. I’m 47 years old and grew up in cal sun. Hope this prevents future SSC

  3. 5 out of 5

    Fred Dogvan

    Age 70, male, excessive sun exposure. The dermatologist suggested “Blue Light” on my face but after the painful experience with this same treatment to my arms, I chose to use fluorouracil. I applied it for two weeks to my face, neck, and ears. On day 13 I went to the dermatologist with fears of open sore infection plus I could barely open my mouth to eat. I was prescribed a topical antibiotic, a topical steroid and Benadryl to reduce swelling, and an OTC product called CeraVe Healing Ointment. The CeraVe’ provided immediate comfort and relief from my misery and allowed my first decent night sleep in over a week. I started by applying CeraVe’ twice a day and then saw an even greater benefit by applying every three hours or so. Aquaphor did not work as well as CeraVe’ for me. I have been restricted from sunlight and leave home only after the sun sets totally (no twilight) to run errands. Looking forward to healthy skin again and daylight hours.

  4. 4 out of 5

    Lucile & Jim

    This is my second round of skin cancer treatment with Flonida – I did a similar timeline of treatment in 2019. I have a history of BCC and SCC with multiple MOHs procedures and other excisions. I can honestly say this treatment is effective; however, it can be painful at times. All of my treatment areas have been scalp, forehead, and cheeks. The cheeks tend to be worse, especially in weeks 3 & 4. This poses a big issue when it comes to shaving. Other than not shaving for a few weeks, has anyone found a way to avoid basically flaying yourself?

  5. 5 out of 5


    The reason we treat our whole face is because if there is precell cancer, or worse, cancer then the fluorouraci finds it!. I look like someone beat me up , but it’s better than the surgery. It is painful if you do have sun damage, but after a month, it should be better. Certainly it’s tolerable. I did have a few side effects. Leg cramps, but better than cancer!!!

Add a review

Your email address will not be published.