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Cutisera® Growth Factor Facial Skin Serum

Growth Factors + Cytokines

(1 customer review)

USD $125.00


Cutisera® Facial Skin Anti-Ageing Serum is developed by Cipla Pharmaceuticals and it is an anti-aging serum containing growth factors and cytokines.

Growth factors and cytokines are a group of specialized proteins with many functions, the most important being skin rejuvenation and repair.

Aging of the skin is mediated by a combination of the effects of time (intrinsic aging) and environmental factors (extrinsic ageing) on skin cells and their extracellular support matrix.

Size: 30g / 1.05oz

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Cipla Pharmaceuticals introducing anti-aging skin care product with human bio-active factors. Cutisera® Facial Skin Anti-Ageing Serum – the next generation bio-engineered skin care product is launched by Cipla Pharmaceuticals and developed by Stempeutics. Cutisera is an anti-aging serum containing growth factors and cytokines. Growth factors and cytokines are a group of specialized proteins with many functions, the most important being skin rejuvenation and repair.

As we age and get exposed to environmental stressors, the production of human growth factors within skin is depleted, giving rise to features of ageing skin. By re-introducing these factors through daily application of Cutisera Serum, damaged skin cells are repaired resulting in rejuvenation of the skin. Ageing of the skin is mediated by a combination of the effects of time (intrinsic ageing) and environmental factors (extrinsic ageing) on skin cells and their extra-cellular support matrix. These are two independent, clinically and biologically distinct, processes that affect the skin structure and function simultaneously. But recent evidence suggests that these two skin ageing processes have common biochemical and molecular pathways, including nuclear and mitochondrial DNA damage, inactivation of growth factors, breakdown of matrix proteins and membrane lipid damage.

While the demand for growth factors to maintain skin health increases with ageing, the levels of endogenous growth factors and their activity are known to decrease in aged skin. A logical approach to reversing the signs of skin ageing is to harness the ability of skin to repair itself and to supplement these healing processes with essential components that have been lost as a result of ageing. The use of growth factors and cytokines in skin rejuvenation and reversal of photoageing is emerging as a novel anti-ageing treatment. Various clinical trials have shown that human growth factors, when applied topically, provide beneficial effects in reducing the signs of facial skin ageing.


Cutisera has been developed using bio-active factors derived from human adult stem cells to enhance the rejuvenation of ageing skin. The active ingredients have been tested for in vitro and in vivo efficacy. The product has been dermatologically tested with human volunteers with features of ageing skin over a period of 3 months, wherein the product was applied twice a day. This human study has demonstrated Cutisera’s effectiveness as a powerful and yet soothing anti-ageing skin care product suitable for all skin types.

Cutisera Serum has been developed using a unique and proprietary patent-pending technology that produces stable key ingredients containing growth factors and cytokines in specified amounts – batch after batch. These results in a consistent high quality product bench marked globally. Improved technology and increased awareness is making people more concerned about their skin, this is driving them to look for skincare products that will not only slowdown the aging process but will also maintain their youthful look for a longer period. It is important to first understand what causes aging and then dealing with the underlying causes. Cutisera Serum exactly does the same. It assists the body’s natural biological repair processes to treat damaged skin and prevent further damage.


Growth factors and cytokines are present in the skin and are responsible for many skin functions. With advancing age, the level of these growth factors and cytokines in the skin decreases and leads to skin ageing. Hence, an external supply of growth factors and cytokines will help replenish their levels and help slowdown or even reverse the signs of ageing.

Cutisera Anti-Ageing Serum is a novel anti-ageing product containing growth factors. The growth factors contained in Cutisera Serum are derived from the conditioned medium of human bone marrow mesenchymal stem cells. Cutisera Anti-Ageing Serum contains the conditioned medium in which stem cells were grown. However, it does not contain any stem cells.

Stem cells of human bone marrow origin are grown in a nutrient medium. During their growth, they release various growth factors and cytokines. This medium is then filtered to remove the cells, cell debris and other components. The filtered and concentrated medium containing mainly the growth factors and cytokines which then used in Cutisera Anti-Ageing Serum.


Individuals with any of these signs of ageing skin – dryness, dull complexion, rough texture, fine lines, wrinkles, and age spots can benefit from the use of Cutisera Anti-Ageing Serum. The visible results of applying Cutisera Anti-Ageing Serum daily include decrease in fine lines and wrinkles, improvement in firmness, decrease in dark spots, and improvement in skin glow and moisturization of the skin.


It will take four to six initial pressings of the actuator/pump for the serum to come out from the container. To apply Cutisera Anti-Ageing Serum dispense 0.5g of Cutisera Anti-Ageing Serum by pressing the pump 2-3 times and apply on the face. Spread uniformly by massaging in a circular motion. Use twice daily, regularly within 2 months. Some visible improvement in the skin occurs by 2-3 months of daily use. The results may vary, depending upon the condition of the skin at the initiation of treatment. After washing the face, Cutisera Anti-Ageing Serum should be applied first. Any other creams or serums applied before Cutisera Anti-Ageing Serum would block reduce the product from being properly absorbed into the skin.


Cipla is a global pharmaceutical company which uses cutting-edge technology and innovation to meet the everyday needs of all patients. For 80 years, Cipla has emerged as one of the most respected pharmaceutical names across more than 150 countries. Its portfolio includes 1500 plus products across therapeutic categories with one quality standard globally. Whilst delivering a long-term sustainable business. Cipla recognises its duty to provide affordable, quality and effective medicines. Cipla’s emphasis on access for patients was recognized globally for the pioneering role played in HIV/AIDS treatment as the first pharmaceutical company to provide a triple combination anti-retroviral (ARV) in Africa at less than one dollar a day and thereby treating many millions of patients since 2001. Cipla’s research and development focuses on developing innovative products and drug delivery systems.

Stempeutics is an advanced clinical stage Biotech Company. It was founded by Manipal Education and Medical Group (MEMG) in 2006 and later entered into a strategic alliance with Cipla in 2009. Stempeutics strength lies in developing innovative stem cell products by nurturing cutting-edge research and clinical applications through dedicated efforts of its highly qualified team. Its goal is to develop novel stem cell drugs addressing major unmet medical needs with a global approach.