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Clingen Forte® Vaginal Capsules

Clindamycin 100mg + Clotrimazole 100mg + Tinidazole 100mg

USD $38.00

Clingen Forte® Vaginal Capsules are used in the Treatment of Syndromic treatment of vaginal discharge.

Vaginal infections can lead to symptoms such as an increase in the quantity of vaginal discharge or a color change. It can also cause a foul smell, itching, or irritation in the vagina. These symptoms can be embarrassing as well as bothersome. Clingen Forte Vaginal Capsule helps in effectively managing these symptoms by killing the organisms responsible for causing an infection of the vagina. Besides using Clingen Forte Vaginal Capsule, always maintain good personal hygiene to avoid any vaginal infection.

Size: 35 Vaginal Capsules
Brand name: C2-PLUS, CCPOLIS-TZ, Clexigard Forte
Title Range Discount
Items: 2 - 4 5%
Items: 5 - 8 10%
Items: 9 + 15%

Description

Clingen Forte® Vaginal Capsule is a combination medicine that is used for the syndromic treatment of vaginal discharge. It fights against infection by stopping the growth of infection-causing microorganisms. It also prevents the further spread of the infection.

Clingen Forte® Vaginal Capsule is to be used as per the label instructions or as suggested by your doctor. This medicine is only for vaginal application. You must wash your hands before and after using it. It is best to use this at bedtime regularly to get the most benefit. If there is any accidental exposure of the medicine to the eyes or mouth, you must wash immediately. For better efficacy of the medicine, the course of the treatment should be completed even if you feel better. Do not use it more than the recommended dose.

Clingen Forte® Vaginal Capsule leads to a few common side effects like frequent urination or mild irritation and burning sensation at the application site. If these side effects do not improve with time or worsen, inform your doctor. In case of any allergic reactions (rashes, itching, swelling, shortness of breath, etc.), it is advised to call for immediate medical help.

Before using it, tell your doctor if you have an underlying disease or are taking medicines for any health condition. The medicines that are used externally usually do not get affected by other medicines, however, you should let your doctor know if you are taking any medicines to ensure safety. Ask your doctor for advice if you are pregnant or breastfeeding. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. During the course of the treatment, you must follow proper personal hygiene for a faster recovery.


Clingen Forte® Vaginal Capsules – Overview

The combination of Clindamycin, Clotrimazole, and Tinidazole in vaginal capsule form is a broad-spectrum antimicrobial formulation used for the treatment of mixed vaginal infections caused by bacteria, fungi, and protozoa. This combination is designed to provide comprehensive relief from vaginal infections by addressing multiple pathogens simultaneously.

Each component plays a distinct role:

  • Clindamycin (100 mg) – An antibiotic that fights bacterial infections, particularly bacterial vaginosis (BV) and other anaerobic bacterial infections.
  • Clotrimazole (100 mg) – An antifungal agent that treats vaginal yeast infections caused by Candida species.
  • Tinidazole (100 mg) – An antiprotozoal and antibacterial agent that is effective against Trichomonas vaginalis (trichomoniasis) and anaerobic bacterial infections.

This triple-action formulation is typically prescribed in softgel vaginal capsule form and provides broad-spectrum coverage, making it ideal for patients with mixed infections.


On-Label Uses of Clindamycin + Clotrimazole + Tinidazole Vaginal Capsules

1. Bacterial Vaginosis (BV)

  • Clindamycin and tinidazole work together to eliminate Gardnerella vaginalis and other anaerobic bacteria responsible for BV.
  • Tinidazole enhances the effectiveness against metronidazole-resistant strains.

2. Vaginal Candidiasis (Yeast Infection)

  • Clotrimazole provides antifungal action, targeting Candida albicans, the most common cause of vaginal yeast infections.

3. Trichomoniasis (Trichomonas vaginalis Infection – STD)

  • Tinidazole is highly effective against trichomoniasis, a common sexually transmitted infection (STI) that causes vaginal discharge, irritation, and discomfort.
  • Clindamycin further supports the eradication of co-infections.

4. Mixed Vaginal Infections

  • Many patients suffer from concurrent bacterial, fungal, and protozoal infections, which this combination is designed to treat simultaneously.

5. Pelvic Inflammatory Disease (PID) – Adjunctive Therapy

  • In some cases, this combination may be prescribed alongside oral or injectable antibiotics for pelvic infections that involve vaginal flora.

Off-Label Uses of Clindamycin + Clotrimazole + Tinidazole Vaginal Capsules

  • Post-Surgical Vaginal Infections – Used to prevent infections after gynecological surgeries or procedures such as hysterectomy.
  • Recurrent Vaginal Infections – May be prescribed as part of a treatment plan for women with chronic or recurrent BV, yeast infections, or trichomoniasis.
  • Vaginal Dysbiosis Treatment – Some clinicians use this combination to restore normal vaginal flora in patients with persistent imbalance.

Why This Combination is Beneficial

  • Broad-Spectrum Action – Treats bacterial, fungal, and protozoal infections at the same time.
  • Targeted Vaginal Delivery – Direct application reduces systemic side effects and maximizes local efficacy.
  • Fast Symptom Relief – Most patients experience relief within 24-48 hours.
  • Single Treatment Regimen – Eliminates the need for multiple separate medications.
  • Effective Against Resistant Strains – Tinidazole improves efficacy in metronidazole-resistant BV and trichomoniasis cases.

Precautions & Warnings

1. Contraindications

  • Allergy or Hypersensitivity to Clindamycin, Clotrimazole, Tinidazole, or other nitroimidazole derivatives.
  • Pregnancy (First Trimester) – Tinidazole may have potential risks for fetal development.
  • Liver Disease – Tinidazole metabolism occurs in the liver; use with caution in hepatic impairment.
  • Neurological Disorders – Tinidazole may cause rare but serious neurological side effects, including seizures.

2. Warnings & Precautions

  • Avoid Alcohol Consumption – Tinidazole can cause a disulfiram-like reaction with alcohol, leading to nausea, vomiting, headache, and flushing.
  • Possible Vaginal Irritation – Mild burning, itching, or increased discharge may occur initially.
  • Interaction with Latex Contraceptives – Clindamycin may weaken condoms and diaphragms, reducing their effectiveness.
  • Recurrent Infections – Patients with chronic vaginal infections should be monitored for underlying conditions like diabetes or immune suppression.
  • Possible Drug Interactions
    • Warfarin (increased risk of bleeding).
    • Lithium (increased toxicity risk).
    • Immunosuppressants (may require dose adjustments).

Frequently Asked Questions (FAQ)

1. How does this combination work?

  • Clindamycin kills anaerobic bacteria responsible for bacterial vaginosis.
  • Clotrimazole eliminates yeast infections caused by Candida.
  • Tinidazole treats protozoal infections like trichomoniasis and enhances antibacterial effects.

2. How should this medication be used?

  • Insert one vaginal capsule at bedtime for 7 days or as prescribed.
  • Do not swallow the capsule; it is for intravaginal use only.
  • Wash hands before and after application.

3. How long does it take for symptoms to improve?

  • Most patients see relief within 24-48 hours, but completing the full treatment course is essential to prevent recurrence.

4. Can I use this medication while on my period?

  • Yes, but avoid using tampons as they may absorb the medication, reducing effectiveness.

5. Can I have sexual intercourse during treatment?

  • It is advised to avoid sexual activity during treatment to prevent reinfection or irritation.

6. Are there any side effects?

Common side effects include:

  • Mild vaginal burning or irritation
  • Increased vaginal discharge
  • Metallic taste in the mouth (due to Tinidazole absorption)
  • Gastrointestinal discomfort (rare)

7. Can I take alcohol while on this medication?

  • No. Tinidazole may cause a severe reaction with alcohol, leading to nausea, vomiting, and headache.
  • Avoid alcohol for at least 72 hours after completing treatment.

8. Is this combination safe for pregnant or breastfeeding women?

  • Not recommended during the first trimester of pregnancy.
  • Breastfeeding mothers should consult a doctor, as Tinidazole passes into breast milk.

9. Can this medication prevent sexually transmitted infections (STIs)?

  • No, this treatment only cures existing infections and does not prevent STIs.
  • Use protection and practice safe sex to reduce the risk of future infections.

10. What should I do if I miss a dose?

  • Insert the missed dose as soon as possible unless it is almost time for the next dose.
  • Do not double dose to make up for a missed one.

Conclusion

The Clindamycin + Clotrimazole + Tinidazole vaginal capsule is an effective and comprehensive treatment for bacterial vaginosis, yeast infections, and trichomoniasis. By combining an antibiotic, antifungal, and antiprotozoal agent, this formulation provides broad-spectrum relief for women suffering from mixed vaginal infections.

This combination is widely prescribed due to its high efficacy, targeted vaginal delivery, and convenience of use. However, it is essential to complete the full course and follow proper hygiene practices to prevent reinfection.

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