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Peroclin® Acne Treatment Once Daily Gel

Clindamycin 1% + Benzoyl Peroxide 2.5% / 5%

(5 customer reviews)

From USD $24.00

Peroclin® Once Daily Gel is indicated for the topical treatment of mild to moderate acne vulgaris.

Peroclin Gel is an alternative to Clindoxyl® Once Daily Gel with Clindamycin Benzoyl Peroxide is used for the treatment of noninflammatory acne.

Size: 15g / 0.53oz
Brand name: Clindoxyl, Benzaclin, Onexton, Acanya, Duac, Neuac, Z-Clinz
Title Range Discount
Items: 2 - 4 5%
Items: 5 - 8 10%
Items: 9 + 15%
SKU: N/A Categories: ,


What is Clindamycin 1% + Benzoyl Peroxide 5% Clindoxyl® Gel

Peroclin (aka Clindoxyl Gel) is manufactured by reputable Ajanta Pharma. Peroclin® Once Daily Gel is a Clindamycin Benzoyl Peroxide Gel has a combination of keratolytic and antibacterial properties providing activity against all the inflamed and non-inflamed lesions of mild to moderate acne vulgaris. The inclusion of benzoyl peroxide reduces the potential for the emergence of organisms resistant to clindamycin. The presentation of both active ingredients in one product is more convenient and ensures patient compliance.

Clindamycin – is a lincosamide antibiotic with bacteriostatic action against gram-positive aerobes and a wide range of anaerobic bacteria. The action of clindamycin is predominantly bacteriostatic although high concentrations may be slowly bactericidal against sensitive strains. Clindamycin activity has been demonstrated clinically in comedones from acne patients at sufficient levels to be active against most strains of Propionibacterium acnes. Clindamycin in-vitro inhibits all Propionibacterium acnes cultures tested (MIC 0.4 mcg/ml). Free fatty acids on the skin surface have been decreased from approximately 14 % to 2 % following the application of clindamycin.

Benzoyl peroxide – is keratolytic acting against comedones at all stages of their development. It is an oxidizing agent with bactericidal activity against Propionibacterium acnes, the organism
implicated in acne vulgaris. Benzoyl peroxide is also believed to be effective in the treatment of acne on account of its anti-inflammatory properties.

Why and when to use Clindamycin Benzoyl Peroxide Gel

This combination product Peroclin® Once Daily Gel contains two medications: clindamycin and benzoyl peroxide. Clindamycin belongs to the family of medications known as antibiotics. Benzoyl peroxide is a medication that has antibacterial effects and is a peeling agent. This combination product is used to treat certain types of acne. It works by killing bacteria that cause acne and by peeling off skin cells. It may take several weeks to months for the improvement of your acne to occur.

Clindamycin benzoyl peroxide gel may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

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Additional Information


Clindamycin Phosphate 1%

Benzoyl Peroxide 5%

Gel base q.s.

Topical gel containing clindamycin (1.2% clindamycin phosphate) at a concentration equivalent to
1% w/w (10 mg/g) and benzoyl peroxide 5% w/w (50 mg/g).

Disodium lauryl sulfosuccinate
Disodium edetate
Silica, colloidal hydrated
Poloxamer 182
Purified water
Sodium hydroxide

5 reviews for Peroclin® Acne Treatment Once Daily Gel

  1. Verna

    Great! I love it. I’ve only been using this medication for about a week and a bit but I can really see the difference. My doctor prescribed me this medication and I was a bit worried about using this “unknown” cream. But this proved me wrong! Very effective. 5/5. Would give a 100/5 if possible haha.

  2. Freya Natty

    I started using this gel in November 2018. It worked instantly for me and all of my spots had completely vanished within a week. I used it every night and it worked perfectly for me for over a year! However, it stopped working in June 2020 for me, and hasn’t worked since. I tried new bottles to see whether one was faulty or expired but it just isn’t effective anymore and my acne has sadly come back. Definitely worth trying however I think the skin must get used to the gel and over time it can become ineffective.

  3. Manisha G.

    I have used Strong Peroclin for 2 months. I have previously used epiduo and experienced bad burning but that was not the case for Peroclin! The drug had a minimal effect for the first month but it is now noticeably clearing my acne. Side effects were very minimal and I am now less depressed and have fewer pimples. I do still have a few pimples. However, I am very pleased with the results so far.

  4. Angelina L.

    I have pretty mild acne, but it really bothered me so I used the medicine and it worked in a few days. Almost all of it is gone now and I’ve been using it for less than a week! I’m happy!

  5. Sia Ju You

    So I’ve always had big painful cysts and small pimples. I turned 27 and thought I’ve had enough, if I haven’t grown out of this now I never will, so went to my GP and got Duac/Peroclin. I started using it every morning and evening, a light layer on my face in Nov, Its now Jan and I have never had such perfect skin. Ever.

    I love this product, changed my life. There are some side effects at the beginning but honestly just be patient. I got SUPER dry red skin around my mouth and chin for 2 weeks, and the acne didn’t go for a month. Its a bit of a tough time as you’re sore from spots as well as dryness but just trust the process! I switched my moisturizer to bio oil gel, which is ok to use on the face, and it helps to reduce spot scars and discoloration.

    It is a heavy duty moisturizer but you need it especially to begin with. Everyone in my life keeps commenting how fresh my skin looks. Only regret is I didn’t use it sooner. Honestly, don’t waste any time go get this stuff. Xx

    Note: please use a disposable towels when using this gel because it discolors everything around!

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