What is Clindamycin 1% + Benzoyl Peroxide 5% Clindoxyl® Gel
Clindoxyl Gel is made by reputable Stiefel Pharmaceuticals. Clindoxyl® Once Daily Gel has a combination of keratolytic and antibacterial properties providing activity against all the inflamed and non-inflamed lesions of mild to moderate acne vulgaris. The inclusion of benzoyl peroxide reduces the potential for the emergence of organisms resistant to clindamycin. The presentation of both active ingredients in one product is more convenient and ensures patient compliance.
Clindamycin – is a lincosamide antibiotic with bacteriostatic action against gram-positive aerobes and a wide range of anaerobic bacteria. The action of clindamycin is predominantly bacteriostatic although high concentrations may be slowly bactericidal against sensitive strains. Clindamycin activity has been demonstrated clinically in comedones from acne patients at sufficient levels to be active against most strains of Propionibacterium acnes. Clindamycin in-vitro inhibits all Propionibacterium acnes cultures tested (MIC 0.4 mcg/ml). Free fatty acids on the skin surface have been decreased from approximately 14 % to 2 % following application of clindamycin.
Benzoyl peroxide – is keratolytic acting against comedones at all stages of their development. It is an oxidizing agent with bactericidal activity against Propionibacterium acnes, the organism
implicated in acne vulgaris. Benzoyl peroxide is also believed to be effective in the treatment of acne on account of its anti-inflammatory properties.
Why and when to use Clindoxyl® Gel
This combination product Clindoxyl® Once Daily Gel contains two medications: clindamycin and benzoyl peroxide. Clindamycin belongs to the family of medications known as antibiotics. Benzoyl peroxide is a medication that has antibacterial effects and is a peeling agent. This combination product is used to treat certain types of acne. It works by killing bacteria that cause acne and by peeling off skin cells. It may take several weeks to months for improvement of your acne to occur.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.