WHAT IS ADACLENE ADAPALENE 0.1% GEL
Adaclene gel produced by reputable and well known Cipla Pharmaceuticals and contains retinoid component – adapalene with 0.1% concentration. Adaclene Adapalene 0.1% Gel is an alternative to famous Differin cream and is a topical gel with similar to vitamin A properties retinoid-like compound and a keratolytic component, it helps the skin to renew itself naturally and used to treat acne and help remove pimples, whiteheads and blackheads and prevent new ones forming. Adaclene Gel with Adapalene 0.1% generally prescribed by dermatologists to treat severe acne in people who are at least 12 years old. It works by decreasing acne formation. Adaclene or Differin Adapalene 0.1% Gel may also be used for purposes other than those listed above, for example as anti-wrinkle or skin care solution.
Avoid getting Adaclene or Differin Adapalene 0.1% Gel in eyes, nos holes, or on lips, if it does – wash with water. Do not use Adaclene or Differin Adapalene 0.1% Gel on sunburned, windburned, dry, chapped, eczema, wounded, irritated, or broken skin. Avoid using products that contain AHA or glycolic acid. Avoid exposure to sunlight or artificial UV rays, always use a sunscreen (minimum SPF 15) and wear protective clothing.
MAIN INGREDIENT – ADAPALENE 0.1%
Adaclene or Differin Adapalene 0.1% Gel contains adapalene, which is a retinoid-like compound in the nucleus of skin cells and changes the way they behave. Acne is often associated with puberty which is when a surge of androgen hormones can over stimulate the sebaceous glands (oil producing glands in hair follicles). Skin cells that are shed from the lining of the hair follicle become trapped in sebum forming a plug below the surface of the skin, clogging the pores, which then attracts bacteria, so that the clogged pores become infected and inflamed, causing an acne outbreak.
Adaclene aka Differin Adapalene 0.1% Gel penetrates deep inside your pores to control the buildup of dead skin and sebum that leads to acne and also blocks the hardening processes of the outer skin layer (keratinisation and cornification) promoting the shedding of old hardened skin cells, while at the same time promoting growth of new skin cells. Adaclene or Differin Adapalene 0.1% Gel also blocks immune cells getting to the site of acne formation which inhibits the inflammatory reaction. This stops pores becoming clogged, infected and inflamed, reducing the outbreak of new pimples, whitehead and blackheads (comedones) as well as clearing up existing blemishes.
Adaclene and Differin (Adapalene 0.1%) Gels and Tazorac (tazarotene) are the two synthetic forms of tretinoin. Adapalene, a derivative of napthoic acid, possesses similar biological properties of tretinoin, but has higher lipophilicity and increased photostability (i.e., stability in light). Unlike tretinoin, adapalene does not bind to proteins within the cell. Instead, adapalene only binds to specific receptors RAR-β and RAR-γ. Adapalene gel 0.1% has efficacy similar to 0.05% isotretinoin, yet with fewer side effects. Its main unique offering is two-fold:
- Adapalene may be combined with oral doxycycline (a penicillin) to treat severe acne.
- At 12 weeks, the combination has been shown to significantly reduce total, inflammatory, and non-inflammatory acne lesions.
- Adapalene is useful in the treatment of melasma, as proven in one study involving Thai users.
WHY TO USE ADACLENE / DIFFERIN ADAPALENE 0.1% GEL
Adaclene Differin Adapalene 0.1% Gel is used to treat acne vulgaris of the face, chest or back, including pimples, whiteheads and blackheads (comedones) and can also be used to treat acne cysts, which can be deep, painful and inflamed. Differin gel 0.1% gel helps combats the processes in the skin that cause clogged pores and lead to pimples and spots associated with acne, helping to clear up these skin blemishes as well as preventing the outbreak of new acne.
HOW TO USE ADACLENE / DIFFERIN ADAPALENE 0.1% GEL
Adaclene Differin Adapalene 0.1% Gel used exactly as your dermatologist has prescribed it for you. Adaclene Differin Adapalene 0.1% Gel is usually applied once daily in the evening. Wash your hands and clean your skin before applying Adaclene gel with adapalene 0.1%, dry the skin well. Apply the gel in a thin layer to the affected skin areas. Avoid application to the areas of skin around eyes, lips and mucous membranes. Use this gel for as many days as it has been prescribed for you even if you think it is not working. Your acne may get slightly worse for a short time when you first start using the gel.
SIDE EFFECTS OF ADACLENE / DIFFERIN ADAPALENE 0.1% GEL
Adaclene Differin Adapalene 0.1% Gel usage should be terminated if the following cases: allergic reactions, hives, difficulty breathing, swelling of your face, lips, tongue, or throat. During your first four weeks of using Adaclene gel with Adapalene 0.1% skin may be dry, red, or scaly, also feels some burning or stinging.