Retino-A Micro® 0.1% Tretinoin Gel is made by reputable Janssen (Johnson&Johnson daughter company). Retino-A Micro 0.1% Tretinoin Gel is a microsphere formulation containing 0.1% of tretinoin (Tretinoin USP – 0.1% w/w as microspheres) for the topical treatment of acne, which uses a patented technology Microsponge® (methyl methacrylate/glycoldimethacrylate crosspolymer porous microspheres for the delivery of active substances to the skin). This is a high quality generic of Retin-A Micro 0.1% Gel made by non-generic brand manufacturer.